Endothelial Cell Protein C Receptor (EPCR) Gene Exon III, 23 Bp Insertion Mutation in the Turkish Pediatric Thrombotic Patients

Thromb Haemost 2002; 88(06): 1068-1069
DOI: 10.1055/s-0037-1613358

Letters to the Editor

Schattauer GmbH

Nejat Akar

¹Pediatric Molecular Genetics Department of Ankara University, Turkey

,

Refik Gökdemir

¹Pediatric Molecular Genetics Department of Ankara University, Turkey

,

Duygu Özel

¹Pediatric Molecular Genetics Department of Ankara University, Turkey

,

Ece Akar

¹Pediatric Molecular Genetics Department of Ankara University, Turkey

References
1 Esmon CT. The Endothelial Cell Protein C Receptor. Thromb Haemost 2000; 83: 639-43.
2 Simmonds RE, Lane DA. Structural and Functional Implications of the hitron/Exon Organisation of the Human Endothelial Cell Protein C/Activated Protein C Receptor (EPCR) Gene: Comparision with the structure of CDl/Major Histocompatibility Complex al and 2 Domains. Blood 1999; 94: 632-41.
3 Biguzzi E, Merati G, Liaw PC, Bucciarelli P, Oganesyan N, Qu D, Gu JM. Fetiveau R, Esmon CT, Manucci PM, Faioni EM A 23 bp insertion in the endoflielial protein C receptor (EPCR) gene impairs EPCR function. Thromb Haemost 2001; 86 (04) 945-8.
4 Akar N, Akar E, Dalgin G, Omurlu K, Sozuoz A, Cin S. Factor V 1691 G-A in Turkish Population. Thromb Haemost 1997; 78: 1527.