Reply to rebuttal: A caution on the use of murine hemophilia models for comparative immunogenicity studies of FVIII products with different protein compositions

Thromb Haemost 2003; 89(06): 1113
DOI: 10.1055/s-0037-1613417

Letters to the Editor

Schattauer GmbH

M Behrmann

,

R Kotitschke

,

M Kloft

References
1 Behrmann M, Pasi J, Saint-Remy JMR. et al. Von Willebrand Factor modulates Factor VIII immunogenicity: Comparative study of different Factor VIII concentrates in a Haemophilia A mouse model. Thromb Haemost 2002; 88: 221-9.
2 Pross HF. Eidinger. Antigenic competition: a review of non-specific antigen-induced suppression. Adv Immunol 1974; 18: 133-68.
3 Insel RA. Potential alterations in immunogenicity by combining or simultaneously administering vaccine components. Ann N Y Acad Sci 1995; 754: 35-47.