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Thromb Haemost 1999; 82(05): 1554-1555
DOI: 10.1055/s-0037-1614871
Letters to the Editor
Schattauer GmbH

Prevalence of the Prothrombin Gene 20210A Mutation in Thrombophilic and Healthy Algerian Subjects

Dominique Helley
1   From Laboratoire Central d’Hématologie, Hôpital Laennec, and INSERM U428, Paris, France
,
Ouerdia Chafa
2   Centre d’Hémobiologie-Transfusion, C.H.U. Alger Centre, Algérie
,
Najat Leila Yaker
2   Centre d’Hémobiologie-Transfusion, C.H.U. Alger Centre, Algérie
,
Abderrezak Reghis
2   Centre d’Hémobiologie-Transfusion, C.H.U. Alger Centre, Algérie
,
Anne-Marie Fischer
1   From Laboratoire Central d’Hématologie, Hôpital Laennec, and INSERM U428, Paris, France
› Institutsangaben
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Received 14. Juni 1999

Accepted after revision 05. Juli 1999

Publikationsdatum:
09. Dezember 2017 (online)

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  • References

  • 1 Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3’-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996; 88: 3698-703.
    PubMedSuche in Google Scholar
  • 2 Rosendaal FR, Doggen CJM, Zivelin A, Arruda VR, Aiach M, Siscovick DS, Hillarp A, Watzke HH, Bernardi F, Cumming AM, Preston FE, Reitsma PH. Geographic distribution of the 20210 G to A prothrombin variant. Thromb Haemost 1998; 79: 706-8.
    Thieme ConnectPubMedSuche in Google Scholar
  • 3 Franco RF, Santos SEB, Elion J, Tavella MH, Zago MA. Prevalence of the G20210A polymorphism in the 3’-untranslated region of the prothrombin gene in different human populations. Acta Haematol 1998; 100: 9-12.
    CrossrefPubMedSuche in Google Scholar
  • 4 Arruda VR, Annichino-Bizzacchi JM, Gonçalves MS, Costa FF. Prevalence of the prothrombin gene variant (nt20210A) in venous thrombosis and arterial disease. Thromb Haemost 1997; 78: 1430-3.
    Thieme ConnectPubMedSuche in Google Scholar
  • 5 Miyata T, Kawasaki T, Fujimura H, Uchida K, Tsushima M, Kato H. The prothrombin gene G20210A mutation is not found among Japanese patients with deep vein thrombosis and healthy individuals. Blood Coagul Fibrinol 1998; 9: 451-2.
    CrossrefPubMedSuche in Google Scholar
  • 6 Lin JS, Shen MC, Tsay W. The mutation at position 20210 in the 3’-untranslated region of the prothrombin gene is extremely rare in Taiwanese Chinese patients with venous thrombophilia. Thromb Haemost 1998; 80: 343.
    Thieme ConnectPubMedSuche in Google Scholar
  • 7 Dilley A, Austin H, Hooper WC, El-Jamil M, Whitsett C, Wenger NK, Benson J, Evatt B. Prevalence of the prothrombin 20210 G-to-A variant in blacks: Infants, patients with venous thrombosis, patients with myocardial infarction, and control subjects. J Lab Clin Med 1998; 132: 452-5.
    CrossrefPubMedSuche in Google Scholar
  • 8 Hessner MJ, Luhm RA, Pearson SL, Endean DJ, Friedman KD, Montgomery RR. Prevalence of prothrombin G20210A, factor V G1691A (Leiden), and methylenetetrahydrofolate reductase (MTHFR) C677T in seven different populations determined by multiplex allele-specific PCR. Thromb Haemost 1999; 81: 733-8.
    Thieme ConnectPubMedSuche in Google Scholar
  • 9 Chafa O, Reghis A, Aubert A, Fischer AM. Prevalence or the FVQ506 (Factor V Leiden) mutation in the normal and thrombophilic Algerian population. Br J Haematol 1997; 97: 688-9.
    PubMedSuche in Google Scholar