Download PDF
Thromb Haemost 2001; 86(05): 1339-1340
DOI: 10.1055/s-0037-1616075
Letters to the Editor
Schattauer GmbH

Genetic Polymorphisms of Angiotensin Converting Enzyme (I/D) and Endothelial Nitric Oxide Synthase (T(-788)C) Genes in Japanese Patients with Myocardial Infarction

Shuichi Takagi
1   National Cardiovascular Center, Suita, Osaka, Japan
,
Yoichi Goto
1   National Cardiovascular Center, Suita, Osaka, Japan
,
Hiroshi Nonogi
1   National Cardiovascular Center, Suita, Osaka, Japan
,
Shunroku Baba
1   National Cardiovascular Center, Suita, Osaka, Japan
,
Naoharu Iwai
1   National Cardiovascular Center, Suita, Osaka, Japan
› Author Affiliations
Further Information

Publication History

Received 19 March 2001

Accepted after revision 05 June 2001

Publication Date:
13 December 2017 (online)

Also available at
    Permissions and Reprints

 

 

  • References

  • 1 Cambien F, Poirier O, Lecerf L, Evans A, Cambou JP, Arveiler D, Luc G, Bard JM, Bara L, Ricard S, Tiret L, Amouyel P, Alhenc-Gelas F, Soubrier F. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992; 359: 641-4.
    CrossrefPubMedSearch in Google Scholar
  • 2 Keavney B, McKenzie C, Parish S, Palmer A, Clark S, Youngman L, Dele-pine M, Lathrop M, Peto R, Collins R. Large-scale test of hypothesised associations between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls. International Studies of Infarct Survival (ISIS) Collaborators. Lancet 2000; 355: 434-42.
    CrossrefPubMedSearch in Google Scholar
  • 3 Nakayama M, Yasue H, Yoshimura M, Shimasaki Y, Kugiyama K, Ogawa H, Motoyama T, Saito Y, Ogawa Y, Miyamoto Y, Nakao K. T-786→C mutation in the 5′-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm. Circulation 1999; 99: 2864-70.
    CrossrefPubMedSearch in Google Scholar
  • 4 Poirier O, Mao C, Mallet C, Nicaud V, Herrmann SM, Evans A, Ruidavets JB, Arveiler D, Luc G, Tiret L, Soubrier F, Cambien F. Polymorphisms of the endothelial nitric oxide synthase gene – no consistent association with myocardial infarction in the ECTIM study. European Journal of Clinical Investigation 1999; 29: 284-90.
    CrossrefPubMedSearch in Google Scholar
  • 5 Iwai N, Katsuya T, Ishikawa K, Mannami T, Ogata J, Higaki J, Ogihara T, Tanabe T, Baba S. Human prostacyclin synthase gene and hypertension: the Suita Study. Circulation 1999; 100: 2231-6.
    CrossrefPubMedSearch in Google Scholar
  • 6 Kazuhiko Ishikawa, Baba S, Katsuya T, Iwai N, Asai T, Fukuda M, Takiuchi S, Fu Y, Mannami T, Ogata J, Higaki J, Ogihara T. T+31C polymorphism of angiotensinogen gene and essential hypertension. Hypertension 2001; 37: 281.
    CrossrefPubMedSearch in Google Scholar