Anakinra bei zwei Kindern mit therapieresistenter systemischer juveniler idiopathischer Arthritis

Angelika Kropp; Hans-Otto Kettner; Hartmut Michels

doi:10.1055/s-0037-1618542

Arthritis und Rheuma, Table of Contents

Arthritis und Rheuma 2006; 26(02): 109-112
DOI: 10.1055/s-0037-1618542

Spezielle Fälle – alltägliche Probleme

Schattauer GmbH

Anakinra bei zwei Kindern mit therapieresistenter systemischer juveniler idiopathischer Arthritis

Anakinra in two children with refractory systemic juvenile idiopathic arthritis

Angelika Kropp

¹Deutsches Zentrum für Kinder- und Jugendrheumatologie (Ärztlicher Direktor: Dr. med. Hartmut Michels)

,

Hans-Otto Kettner

¹Deutsches Zentrum für Kinder- und Jugendrheumatologie (Ärztlicher Direktor: Dr. med. Hartmut Michels)

,

Hartmut Michels

¹Deutsches Zentrum für Kinder- und Jugendrheumatologie (Ärztlicher Direktor: Dr. med. Hartmut Michels)

› Author Affiliations

Abstract

Zusammenfassung

Zwei Kinder mit therapieresistenter systemischer juveniler idiopathischer Arthritis wurden erfolgreich mit Anakinrabehandelt. Die Tagesdosis lag zwischen 0,6 und 1,6 mg/kg s.c. Eine Dosisreduktion um 50 Prozent führte nicht zu einer Reaktivierung. Lokalreaktionen an der Injektionsstelle besserten sich dosisabhängig.

Summary

Two children with refractory systemic juvenile idiopathic arthritis have been successfully treated with Anakinra. The effective dosage varied between 0,6 mg and 1,6 mg/kg body weight/day subcutaneously. No relapse after a dose reduction of 50% has been seen. Skin reactions on injection sites were dose-dependent and could be diminished to a tolerable degree by dose reduction.

Schlüsselwörter

Systemische juvenile idiopathische Arthritis - Anakinra - Nebenwirkungen

Keywords

Systemic juvenile idiopathic arthritis - Anakinra - side effects

Full Text

References

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