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Tierarztl Prax Ausg K Kleintiere Heimtiere 2005; 33(06): 401-406
DOI: 10.1055/s-0037-1622498
Hund/Katze
Schattauer GmbH

Möglichkeiten der Diagnostik von Tumorerkrankungen am Magen-Darm-Trakt

Diagnostic techniques for identifying tumors of the gastrointestinal tract
Daniela Simon
1   Aus der Klinik für kleine Haustiere (Direktor: Prof. Dr. I. Nolte) der Stiftung Tierärztliche Hochschule Hannover
,
F. Meneses
1   Aus der Klinik für kleine Haustiere (Direktor: Prof. Dr. I. Nolte) der Stiftung Tierärztliche Hochschule Hannover
,
I. Nolte
1   Aus der Klinik für kleine Haustiere (Direktor: Prof. Dr. I. Nolte) der Stiftung Tierärztliche Hochschule Hannover
› Author Affiliations
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Publication History

Publication Date:
05 January 2018 (online)

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Zusammenfassung

Der Artikel gibt eine Übersicht über die Möglichkeiten der Diagnostik von Tumoren des Magen-Darm-Trakts bei Hund und Katze, die oftmals eine diagnostische Herausforderung darstellen. Häufig weisen die Patienten unspezifische Symptome auf. Sowohl für die Prognose als auch für die Therapieoptionen sind Herkunft und Lokalisation, Ausbreitung sowie Dignität des Tumors wesentlich. Daher werden differenzierte diagnostische Verfahren zur Erkennung des Tumors benötigt. Diese Verfahren sind nicht notwendigerweise invasiv, aber vielfach von einem hohen apparativen Aufwand verbunden oder sie erfordern zur Ergänzung spezielle labordiagnostische Techniken. Die Kombination verschiedener bildgebender Verfahren mit differenzierter zytologischer oder histologischer Diagnostik bietet auf minimal invasivem Weg zurzeit die größte diagnostische Sicherheit und somit zunehmend bessere Informationen für Prognosestellung und Therapie.

Summary

This article reviews the different diagnostic techniques for tumors of the gastrointestinal tract. Tumors of the gastrointestinal tract in dogs and cats frequently represent a diagnostic challenge. Patients often display unspecific clinical signs. However, prognoses as well as applicable therapeutic options strongly depend on the type of tumor, its organ of origin and its distribution throughout the abdominal cavity. Therefore, specific diagnostic techniques are needed. They are not necessarily invasive but often require a specialized technical equipment or additional laboratory techniques. The combination of different imaging techniques with cytologic and/or histologic investigations represents minimally invasive procedures with good diagnostic security leading to improved information for an evaluation of prognosis and therapeutic options.

Schlüsselwörter

Tumor - Magen-Darm-Trakt - Diagnostik - Hund - Katze

Key words

Tumor - Gastrointestinal tract - Diagnostics - Dog - Cat
 

  • Literatur

  • 1 Beneduce L, Castaldi F, Marino M, Tono N, Gatta A, Pontisso P, Fassina G. Improvement of liver cancer detection with simultaneous assessment of circulating levels of free alpha-fetoprotein (AFP) and AFP-IgM complexes. Int J Biol Markers 2004; 19 (02) 155-9.
    CrossrefPubMedGoogle Scholar
  • 2 Bomhard von D. Tumoren des alimentären Systems. In: Praxis der Onkologie bei Hund und Katze. Epidemiologie. Nolte I, Nolte M. Hrsg. Stuttgart: Enke; 2001: 62-78.
    Google Scholar
  • 3 Brannigan M, Burns PN, Wilson SR. Blood flow patterns in focal liver lesions at microbubble-enhanced US. Radiographics 2004; 24 (04) 921-35.
    CrossrefPubMedGoogle Scholar
  • 4 Cranshaw J, Berg J, Sardinas JC, Engler SJ, Rand WM, Ogilvie GK, Spodnick GJ, Vail DM, Henderson RA. Prognosis for dogs with nonlymphomatous, small intestinal tumors treated by surgical excision. J Am Anim Hosp Assoc 1998; 34: 451-6.
    CrossrefPubMedGoogle Scholar
  • 5 Cribb AE. Feline gastrointestinal adenocarcinoma: A review and retrospective study. Can VetJ 1988; 29: 233-5.
    PubMedGoogle Scholar
  • 6 Clifford CA, Pretorius ES, Weisse C, Sorenmo KU, Drobatz KJ, Siegelman ES, Solomon JA. Magnetic resonance imaging of focal splenic and hepatic lesions in the dog. J Vet Intern Med 2004; 18 (03) 330-8.
    CrossrefPubMedGoogle Scholar
  • 7 Couto CG, Rugers HC, Sherding RG, Rojko J. Gastrointestinal lymphoma in 20 dogs. A retrospective study. J Vet Int Med 1989; 03: 73-8.
    CrossrefPubMedGoogle Scholar
  • 8 Decker D, Bollmann R, Hirner A, Stratmann H. Increased CA-19–9 caused by a splenic cyst: a rare differential diagnosis. Zentralbl Chir 1998; 123 (07) 855-7.
    PubMedGoogle Scholar
  • 9 Easton S. A retrospective study into the effects of operator experience on the accuracy of ultrasound in the diagnosis of gastric neoplasia in dogs. Vet Radiol Ultrasound 2001; 42: 47-50.
    CrossrefPubMedGoogle Scholar
  • 10 Forsberg F, Johnson DK, Merton DA, Li JB, Losco PE, Hagen EK, Goldberg BB. Contrast-enhanced transrectal ultrasonography of a novel canine prostate cancer model. J Ultrasound Med 2002; 21 (09) 1003-13.
    CrossrefPubMedGoogle Scholar
  • 11 Giroux A, Jones JC, Bohn JH, Duncan RB, Waldron DR, Inzana KR. A new device for stereotactic CT-guided biopsy of the canine brain: design, construction, and needle placement accuracy. Vet Radiol Ultrasound 2002; 43 (03) 229-36.
    CrossrefPubMedGoogle Scholar
  • 12 Hagen EK, Forsberg F, Liu JB, Gomella LG, Aksnes AK, Merton DA, Johnson D, Goldberg BB. Contrast-enhanced power Doppler imaging of normal and decreased blood flow in canine prostates. Ultrasound Med Biol 2001; 27 (07) 909-13.
    CrossrefPubMedGoogle Scholar
  • 13 Hahn KA, Richardson RC. Detection of serum alpha-fetoprotein in dogs with naturally occurring malignant neoplasia. Vet Clin Pathol 1995; 24 (01) 18-21.
    CrossrefPubMedGoogle Scholar
  • 14 Hirschberger J. Zytologie von Körperhöhlenergüssen. Tierarztl Prax 1995; 23 (02) 192-9.
    PubMedGoogle Scholar
  • 15 Huang QJ, Xu Q, Wang XN, Zhang LL. Spiral multi-phase CT in evaluating resectability of pancreatic carcinoma. Hepatobiliary Pancreat Dis Int 2002; 01 (04) 614-9.
    PubMedGoogle Scholar
  • 16 Iwasaki Y, Arai K, Katayanagi S, Takahashi K, Yamaguchi T, Matsumoto H, Miyamoto H. Biomarkers for neoplasmas in digestive organs Gan To Kagaku Ryoho. 2004; 31 (07) 1015-20.
    PubMedGoogle Scholar
  • 17 Koblik PD, LeCouteur RA, Higgins RJ, Bollen AW, Vernau KM, Kortz GD, Ilkiw JE. CT-guided brain biopsy using a modified Pelorus Mark III stereotactic system: experience with 50 dogs. Vet Radiol Ultrasound 1999; 40 (05) 434-40.
    CrossrefPubMedGoogle Scholar
  • 18 Lechowski R, Jagielski D, Hoffmann-Jagielska M, Zmudzka M, Winnicka A. Alpha-fetoprotein in canine multicentric lymphoma. Vet Res Commun 2002; 26 (04) 285-96.
    CrossrefPubMedGoogle Scholar
  • 19 Lee KH, O’Malley ME, Haider MA, Hanbidge A. Triple-phase MDCT of hepatocellular carcinoma. AJR Am J Roentgenol 2004; 182 (03) 643-9.
    CrossrefPubMedGoogle Scholar
  • 20 Lowseth LA, Gillett NA, Chang IY, Muggenburg BA, Boecker BB. Detection of serum alpha-fetoprotein in dogs with hepatic tumors. J Am Vet Med Assoc 1991; 199 (06) 735-41.
    PubMedGoogle Scholar
  • 21 MacVean DW, Monlux AW, Anderson Jr PS, Silberg SL, Roszel JF. Frequency of canine and feline tumors in a defined population. Vet Pathol 1978; 15 (06) 700-15.
    CrossrefPubMedGoogle Scholar
  • 22 Mahoney OM, Moore AS, Cotter SM, Engler SJ, Brown D, Penninck D. Alimentary lymphoma in the cat: 28 cases (1988–1993). J Am Vet Med Assoc 1995; 207: 1593-8.
    PubMedGoogle Scholar
  • 23 Meneses F, Gerdwilker A, Meyer-Lindenberg A, Nolte I. Three-dimensional models of congenital portosystemic shunts in dogs based on helical CT: Technique and preliminary experience. J Small Anim Pract (in press).
    PubMedGoogle Scholar
  • 24 Paoloni MC, Penninck DG, Moore AS. Ultrasonographic and clinicopathologic findings in 21 dogs with intestinal adenocarcinoma. Vet Radiol Ultrasound 2002; 43 (06) 562-7.
    CrossrefPubMedGoogle Scholar
  • 25 Penninck D, Smyers B, Webster CR, Rand W, Moore AS. Diagnostic value of ultrasonography in differentiating enteritis from intestinal neoplasia in dogs. Vet Radiol Ultrasound 2003; 44 (05) 570-5.
    CrossrefPubMedGoogle Scholar
  • 26 Quaia E, Stacul F, Gaiani S, Ricci P, Passariello R, Curzio D, Pozzi RMucelli. Comparison of diagnostic performance of unenhanced vs SonoVue-enhanced ultrasonography in focal liver lesions characterization. The experience of three italian centers. Radiol Med (Torino) 2004; 108 (1–2): 71-81.
    PubMedGoogle Scholar
  • 27 Sellon RK, Bissonnette K, Bunch SE. Long-term survival after total gastrectomy for gastric adenocarcinoma in a dog. J Vet Int Med 2006; 10: 333-5.
    PubMedGoogle Scholar
  • 28 Suh M, Coakley FV, Qayyum A, Yeh BM, Breiman RS, Lu Y. Distinction of renal cell carcinomas from high-attenuation renal cysts at portal venous phase contrast-enhanced CT. Radiology 2003; 228 (02) 330-4.
    CrossrefPubMedGoogle Scholar
  • 29 Trigo FJ, Thompson H, Breeze RG. The pathology of liver tumors in the dog. J Comp Pathol 1982; 92: 21-39.
    CrossrefPubMedGoogle Scholar
  • 30 Walter MC, Matthiesen DT, Stone EA. Pylorectomy and gastroduodenostomy in the dog: Technique and clinical results in28 cases. J Am Vet Med Assoc 1985; 187: 909-14.
    PubMedGoogle Scholar
  • 31 Whelan HT, Clanton JA, Wilson RE, Tulipan NB. Comparison of CT and MRI brain tumor imaging using a canine glioma model. Pediatr Neurol 1988; 04 (05) 279-83.
    CrossrefPubMedGoogle Scholar
  • 32 Withrow SJ, Thamm DH, Phillips BS. Tumors of the gastrointestinal tract. In: Small Animal Clinical Oncology. Withrow SJ, MacEwen EG. eds. Philadelphia: Saunders; 2001: 305-353.
    Google Scholar
  • 33 Yamada T, Fujita M, Kitao S, Ashida Y, Nishizono K, Tsuchiya R, Shida T, Kobayashi K. Serum alpha-fetoprotein values in dogs with various hepatic diseases. J Vet Med Sci 1999; 61 (06) 657-9.
    CrossrefPubMedGoogle Scholar
  • 34 Zwingenberger AL, Schwarz T. Dual-phase CT angiography of the normal canine portal and hepatic vasculature. Vet Radiol Ultrasound 2004; 45 (02) 117-24.
    CrossrefPubMedGoogle Scholar