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Nuklearmedizin 1976; 15(02): 77-79
DOI: 10.1055/s-0038-1624938
Originalarbeiten — Original Articles
Schattauer GmbH

Calcium Metabolism in Children Suffering from Homozygous ß-Thalassaemia after Oral Administration of 47Ca

Kalzium-Stoffwechsel bei Kindern mit homozygoten ß-Thalassämie nach oraler Verabreichung von 47Ca
D. Liakakos
1   From the 2nd Department of the Childrens’ Hospital „Aglaia Kyriakou” (Head: Ass. Prof. D. Liakakos) and the Department of Radioisotopes of the Alexandra Hospital (Head: Prof. B. Malamos), Athens
,
P. Ylachos
1   From the 2nd Department of the Childrens’ Hospital „Aglaia Kyriakou” (Head: Ass. Prof. D. Liakakos) and the Department of Radioisotopes of the Alexandra Hospital (Head: Prof. B. Malamos), Athens
,
Ch. Anoussakis
1   From the 2nd Department of the Childrens’ Hospital „Aglaia Kyriakou” (Head: Ass. Prof. D. Liakakos) and the Department of Radioisotopes of the Alexandra Hospital (Head: Prof. B. Malamos), Athens
,
C. Constantinides
1   From the 2nd Department of the Childrens’ Hospital „Aglaia Kyriakou” (Head: Ass. Prof. D. Liakakos) and the Department of Radioisotopes of the Alexandra Hospital (Head: Prof. B. Malamos), Athens
,
I. Tsakalosos
1   From the 2nd Department of the Childrens’ Hospital „Aglaia Kyriakou” (Head: Ass. Prof. D. Liakakos) and the Department of Radioisotopes of the Alexandra Hospital (Head: Prof. B. Malamos), Athens
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Publication History

Received:24 October 1975

Received:03 October 1975

Publication Date:
11 January 2018 (online)

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Summary

The study of calcium metabolism in ten thalassaemic children comperatively with controls after oral administration of 47Ca has shown diminished intestinal absorption. It is suggested that this finding is propably related in part with the pathogenesis of the osteoporosis in thalassaemia.

Das Studium des Metabolismus des Kalziums bei zehn Thallassämia-major-kranken Kindern in Vergleich zu Kontroll-Kindern nach oraler Gabe von 47Ca zeigte verminderte Urinabgabe und verminderte Darmaufnahme. Es wird angenommen, daß dieser Befund vielleicht zum Teil mit der Pathogenese der Osteoporose bei Thalassämia major zusammenhängt.

 

  • References

  • 1 Caffey I. Cooley’s Anemia: A review of the roentgenographic findings in the skeleton. Amer. J. Roentgen 1957; 78: 381.
    PubMedGoogle Scholar
  • 2 Constantinides C, Binopoulos D, Dracos C, Malamos B. Radioaktive Isotope in Klinik und Forschung. Siebentes internationales Symposion in Bad Gastein. Österreich: 1966: 420.
    Google Scholar
  • 3 Harrison M, Fracer R, Mullan B. Calcium metabolism in osteoporosis. Lancet I: 1015 1961;
    PubMedGoogle Scholar
  • 4 Jowsey J, Gershon-Cohen J. Effect of dietary calcium levels on production and reversal of experimental osteoporosis in cats. Proc. Soc. Exp. Biol. Med 1964; 116: 437.
    CrossrefPubMedGoogle Scholar
  • 5 Muller-Eberhard U, Erlandson M. E, Ginn H. E, Smith C. H. Effect of trisodium calcium diethylenetriaminepentaacetate on bivalent cations in thalassemia major. Blood 1963; 22: 209.
    PubMedGoogle Scholar
  • 6 Nordin B. E. C. The pathogenesis of osteoporosis. Lancet 1961; I: 1011.
    PubMedGoogle Scholar