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Nervenheilkunde 2010; 29(11): 758-760
DOI: 10.1055/s-0038-1628836
Kognitive Störungen
Schattauer GmbH

Bildgebende Verfahren in der Diagnostik von Demenzerkrankungen

Brain imaging in the diagnostic process of dementia
F Jessen
1   Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Bonn
› Author Affiliations
Further Information

Publication History

Eingegangen am: 21 June 2010

angenommen am: 16 August 2010

Publication Date:
31 January 2018 (online)

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Zusammenfassung

Die zerebrale Bildgebung hat in der ätiologischen Diagnostik von Demenzerkrankungen die Funktion z. B. chirurgisch behandelbare Ursachen einer Demenz aufzudecken. Zusätzlich trägt sie zur Differenzialdiagnose von primären Demenzerkrankungen bei. Neurodegenerative Erkrankungen sind durch typische Atrophiemuster gekennzeichnet. Vaskuläre Läsionen können sensitiv mit der MRT erfasst werden. Zahlreiche neue MRT-Verfahren befinden sich in der klinischen Entwicklung. Als nuklearmedizinisches Verfahren ist insbesondere die 18F-Fluordesoxyglukose (FDG)-PET wertvoll. Die zukünftige klinische Relevanz von Amyloid-PET wird mit großer Wahrscheinlichkeit sehr hoch sein.

Summary

In the diagnostic process of dementia brain imaging is needed to detect causes of dementia that may be reversible by for example surgical interventions. Also brain imaging helps in differentiating primary causes of dementia. Neurodegenerative disorders are characterized by typical patterns of atrophy. Vascular damage can be detected sensitively with MRI. Among nuclear medicine techniques, 18F-Fluordesoxyglucose (FDG)-PET is particularly valuable. The importance of amyloid PET in clinical practice in the future will be high.

Schlüsselwörter

Demenz - Alzheimer - MRT - PET

Keywords

Dementia - Alzheimer’s disease - MRI - PET
 

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