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Nuklearmedizin 1988; 27(04): 154-156
DOI: 10.1055/s-0038-1629448
Review Articles
Schattauer GmbH

The Influence of Experimental Conditions on the Preparation of 99mTc-Pyrrolidino-Methyl Tetracycline [99mTc-PMT] in the Form of an Instant Kit

Der Einfluss des Experimentellen Bedingungen für die Vorbereitung von 99mTc-Pyrrolidino-Methyl Tetracyclin [99mTc-PMT] in der Form eines Instant-Kits
Y. F. Shafiq
1   From the Radioisotope Production Department, Nuclear Research Centre, and the Ibn Al-Nafis Cardiovascular Teaching Hospital, Baghdad, Iraq
,
M. H. S. Al-Hissoni *
1   From the Radioisotope Production Department, Nuclear Research Centre, and the Ibn Al-Nafis Cardiovascular Teaching Hospital, Baghdad, Iraq
,
M. H. Jassim *
1   From the Radioisotope Production Department, Nuclear Research Centre, and the Ibn Al-Nafis Cardiovascular Teaching Hospital, Baghdad, Iraq
› Author Affiliations
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Publication History

Received: 15 July 1987

in revised form: 18 December 1987

Publication Date:
04 February 2018 (online)

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The effects of varying the experimental conditions of the preparation of the renal scanning agent 99mTc-PMT on its organ distribution have been investigated. The stability of 99mTc-PMT was determined in vitro. A procedure for the preparation of this agent is recommended.

Zusammenfassung

Die Auswirkungen einer Änderung der experimentellen Bedingungen der Herstellung von 99mTc-PMT zur Szintigraphie der Nieren auf dessen Organverteilung wurden untersucht. Die Stabilität des 99mTc-PMT wurde in vitro bestimmt. Eine Vorgangsweise zur Herstellung dieses Präparates wird empfohlen.

 

  • REFERENCES

  • 1 Boyd R E, Robson J, Hunt E C. et al. 99mTc-gluconate complexes for renal scintigraphy. Br J Radiol 1973; 46: 604.
    CrossrefPubMedSearch in Google Scholar
  • 2 Dewanjee M K, Fliegel C P, Treves S, Davis D. 99mTc-labelled tetracycline: a new radiopharmaceutical for renal imaging. J Nucl Med 1972; 13: 427.
    Search in Google Scholar
  • 3 Fliegel C P, Dewanjee M K, Holman B L. et al. 99mTc tetracycline as a kidney and gallbladder imaging agent. Radiology 1974; 110: 407.
    CrossrefPubMedSearch in Google Scholar
  • 4 Holman L B, Dewanjee M K, Idoine J. et al. Detection and localization of experimental myocardial infarction with 99mTc tetracycline. J Nucl Med 1973; 14: 595.
    PubMedSearch in Google Scholar
  • 5 Holman B L, William D K, Dewanjee M K. et al. Tumor detection and localization with 99mTc tetracycline. Radiology 1974; 112: 147.
    CrossrefPubMedSearch in Google Scholar
  • 6 Lin T H, Khentigan A, Winchell H S. A 99mTc-chelate substitute for organoradiomercurial renal agents. J Nucl Med 1974; 15: 34.
    PubMedSearch in Google Scholar
  • 7 Robinson G D, Battaglia D J. 99mTechnetium tetracycline: preparation, biological dynamics and uptake in damaged and normal skeletal muscle. Int J Appl Radiat Isot 1973; 26: 147.
    Search in Google Scholar
  • 8 Shafiq Y F. et al. Unpublished data.
  • 9 Zmbova B, Zivanov-Stakic D, Tadzer I, Bogdanova V. The preparation and control of pyrrolidino-methyl tetracycline labeled with 99mTc. Int J Appl Radiat Isot 1978; 29: 359.
    CrossrefPubMedSearch in Google Scholar