Nuklearmedizin 1988; 27(05): 195-199
DOI: 10.1055/s-0038-1629450
Review Articles
Schattauer GmbH

Radioisotope Evidence of Varying Transit of Solid Food in Gastrectomized Patients with and without Dumping Syndrome

F. Palermo
,
F. Boccaletto
,
M. Magalini
*   From the Servizio di Medicina Nucleare, the Servizio di Gastroen- terologia, Ospedale Regionale, Treviso, Italy
,
G. Chiara
**   And the I. Divisione Chirurgica, Ospedale Regionale, Treviso, Italy
,
T. Tommaseo
**   And the I. Divisione Chirurgica, Ospedale Regionale, Treviso, Italy
,
L. Dapporto
**   And the I. Divisione Chirurgica, Ospedale Regionale, Treviso, Italy
› Author Affiliations
Further Information

Publication History

Received: 14 December 1987

Publication Date:
04 February 2018 (online)

Of 29 Billroth II gastrojejunostomy patients studied by scintigraphy, 11 were dumpers and 18 were non-dumpers; of 20 controls, 11 were patients with different gastric complaints and 9 volunteers with no history of gastrointestinal pathology. The tracer used was human albumin microspheres labelled with 99mTc, mixed thoroughly with a fresh scrambled egg, cooked as an omelet and eaten as a sandwich with white toasted bread. The transit and emptying of the radiolabelled meal in the gastric and derivative loop areas were followed with a gamma camera 90-120 min. In the dumpers half-emptying times were significantly shorter than in the controls; in the non-dumpers they were even shorter. Dynamic selective analysis of the radiolabelled food transit through derivative afferent and efferent loops showed, on the other hand, different patterns for the two groups of gastroresected patients: the progression of propulsive waves was very irregular and constantly hyperperistaltic only in the dumpers.

Zusammenfassung

Von 29 Patienten, die sich der Billroth II Gastrojejunostomie unterzogen hatten, wiesen 11 das Entleerungssyndrom auf und 18 waren NonDumpers; von 20 Kontrollpatienten klagten 11 über verschiedene Magenbeschwerden und 9 waren Freiwillige ohne gastrointestinale Pathologie. 99mTc-markierte Humanalbumin-Mik- rosphären wurden gründlich mit einem frischen Rührei vermischt, als Omelett gekocht und als Sandwich auf getoastetem Weißbrot verabreicht. Der Transit der so gekennzeichneten Mahlzeit durch den Magen und die anschließenden Darmschlingen wurde mittels Gamma-Kamera während 90-120 min beobachtet. Bei der ersten Gruppe der Gastrektomiepatienten waren die Halbentleerungszeiten deutlich kürzer als bei den Kontrollpatienten und bei den Patienten ohne Dumping-Syndrom noch kürzer. Die dynamisch selektive Analyse des Transits der markierten Mahlzeit durch die zu- und abführenden Darmschlingen zeigte dagegen unterschiedliche Muster für die beiden Gruppen der Gastrektomiepatienten: das Fortschreiten der propulsiven Wellen war nur bei den Patienten mit Dumping-Syndrom unregelmäßig und konstant hyperperistaltisch.

 
  • REFERENCES

  • 1 Aeberhard P, Steudler G, Noelpp U, Rosier H. Mean transit time of solid test meals in gastric emptying. Digest 1977; 15: 361-72.
  • 2 Duthie H L, McKeller N J. Radiological appearances in the post-gastrectomy dumping syndrome. Br J Radiol 1960; 33: 171-7.
  • 3 Harvey R F, Mackie D B, Brown N J C, Keeling D H, Davies W T. Measurement of gastric emptying time with a gamma camera. Lancet 1970; i: 16-8.
  • 4 Heading R C, Tothill P, McLaughlin G P, Shearman D J C. Gastric emptying rate measurement in man. A double isotope scanning technique for simultaneous study of liquid and solid components of meal. Gastroenterology 1976; 71: 45-50.
  • 5 Horowitz M, Cook D J, Collins P J, Harding P E, Shearman D J. The application of techniques using radionuclides to the study of gastric emptying. Surg Gyn Obst 1982; 155: 737-44.
  • 6 Hulme-Moir I. The role of altered gastric emptying in initiation of clinical dumping. Scand J Gastroent 1979; 14: 463-7.
  • 7 Knight L C, Fischer R S, Malmud L S. Comparison of solid food markers in gastric emptying studies. In: Raynaud C. ed. Nuclear Medicine and Biology Advances. Oxford: Pergamon; 1983: 2407-10.
  • 8 MacGregor I L, Martin P, Meyer J H. Gastric emptying of solid food in normal man and after subtotal gastrectomy and truncal vagotomy with pyloroplasty. Gastroenterology 1977; 72: 206-11.
  • 9 Madsen P, Kroneberg O, Feldt-Rasmussen K. The gastric emptying and small intestinal transit after highly selective vagotomy without drainage and selective vagotomy with pyloroplasty. Scand J Gastroent 1973; 08: 541-3.
  • 10 Malagelada J R. The regulation of gastric emptying in health and disease. View Dig Dis 1981; 11: 13-7.
  • 11 Malmud L D, Fischer R S, Knight L C, Rock E. Scintigraphic evaluation of gastric emptying. Sem Nucl Med 1982; 12: 116-25.
  • 12 Meyer J H, MacGregor I L, Gueller R, Martin P, Cavalieri R. 99m-Tc-tagged chicken livers as a marker of solid food in the human stomach. Am J Dig Dis 1976; 21: 296-304.
  • 13 Sheiner H Y, Quinlan M F, Thompson I J. Gastric motility and emptying in normal and post-vagotomy subjects. Gut 1980; 21: 753-9.
  • 14 Taillefer R, Douesnard M, Beauchamp G. Guimond Comparison of technetium 99m sulfur colloid and technetium 99m albumin colloid labeled solid meals for gastric emptying studies. Clin Nucl Med 1987; 12: 597-600.
  • 15 Van Dam A P. The gamma camera in clinical evaluation of gastric emptying. Radiology 1974; 110: 155-7.