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DOI: 10.1055/s-0038-1637462
PREVALENCE OF INTESTINAL METAPLASIA AND DYSPLASIA IN PATIENTS WITH VERRUCOUS GASTRITIS AT A TERTIARY REFERRAL HOSPITAL
Publikationsverlauf
Publikationsdatum:
27. März 2018 (online)
Aims:
Verrucous Gastritis (VG), also known as chronic erosive gastritis is a type of gastritis with characteristic endoscopic features such as numerous small elevated lesions with a central umbilical-like depression (“octopus sucker” gastritis). The association between verrucous gastritis and gastric dysplasia is not well known, as well as the risk factors for the development of this entity.
Our aims were to study the prevalence of intestinal metaplasia and dysplasia in patients with verrucous gastritis, and to describe the prevalence of H. pylori infection and family history of gastric neoplasia in this patients.
Methods:
Demographic, clinical, endoscopic and histological data were collected from all patients diagnosed of verrucose gastritis during upper endoscopy at a terciary referral hospital in Catalonia from October 2014 to October 2017. All the endoscopies were performed with a high resolution non-magnifying gastroscope by an experienced endoscopist in recognition of gastric lesions.
Results:
42 patients were included. The mean age was 59.9 years (38 – 88, SD 11,5) with men being 45.2%. H. pylori infection was present in 33.3%, 43% of patients were smokers and 16.7% had family history of gastric cancer. Intestinal metaplasia was found in 86% and dysplasia/early neoplasia in 31% of patients. The data is summarized in the table.
Histology |
N (%) |
Low Grade Dysplasia |
7 (53) |
High Grade Dysplasia |
5 (38,5) |
Non-invasive Carcinoma |
1 (1,8) |
Conclusions:
The presence of VG might allow the recognition of a gastric mucosa at risk for the development of dysplasic lesions, however larger size prospective studies would be necessary to establish associations.
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