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DOI: 10.1055/s-0038-1637680
THE RECURRENCE RISK OF EARLY GASTRIC CANCER FOLLOWING ENDOSCOPIC RESECTION
Publication History
Publication Date:
09 May 2018 (online)
Aims:
Early gastric cancer(EGC) confined to mucosa and upper 1/3 of submucosa can be treated safely with endoscopic resection(ER) such as endoscopic submucosal dissection or endoscopic mucosal resection. Long term clinical outcome in terms of cancer recurrence is still a major concern about endoscopic resection.
Methods:
Patients with T1 gastric cancer were enrolled consecutively from September 2006 to October 2015 in a single academic hospital, Seoul, Korea. Electronic medical records were analyzed retrospectively.
Results:
A total of 126 patients were diagnosed with T1 stage gastric cancer and treated with endoscopic resection. Cancer histology and size, Helicobacter infection, lympho-vascular invasion of cancer, smoking and alcohol were included for analysis. The median follow up period was 26.7 months. During a follow up, a total of 10 patients (7.94%) developed recurrence. Piecemeal resection (odds ratio [OR] 7.067, 95% confidence interval [CI] 1.706 – 29.285, P = 0.007) and tumor-positive resection margin (OR 33.292, 95% CI 7.064 – 159.904, P < 0.0001) were significant risk factors for cancer recurrence after endoscopic resection.
Conclusions:
The gastric cancer recurrence of T1 disease was 7.94% during 26.7 months following endoscopic resection. Piecemeal resection and resection margin involvement were the risk factors for recurrence after endoscopic resection for EGC.
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