Defective Collagen-Induced Platelet Aggregation in a Normal Population

Summary

Systemic studies on platelet functions of normal healthy individuals were carried out in two independent centres. Both samples of 40 volunteers comprised several individuals (Amsterdam 3 and Utrecht 5 individuals) with a syndrome consisting of an absent collagen-induced platelet aggregation, a reversible ADP-aggregation and frequently a decreased platelet retention in the glass bead column. Occasionally the platelet factor-3 availability was decreased.

• References

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