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Thromb Haemost 1960; 4(03): 462-472
DOI: 10.1055/s-0038-1654528
DOI: 10.1055/s-0038-1654528
Originalarbeiten — Original Articles — Travaux Originaux
The Effects of Sodium Citrate and an Excess of Plasminogen on Fibrinolytic Agents[*]
Further Information
Publication History
Publication Date:
17 June 2018 (online)
Summary
1. The presence of citrate in the normal fibrin enhanced the fibrinolytic activity of plasminogen activators, including trypsin. The effect of proteases (on normal or on heated fibrin, containing citrate) was not significantly influenced.
2. The effect of plasminogen activators was also increased when excess of plasminogen was present in the normal fibrin plates.
3. Fumaric acid and maleic acid belong to the polycarboxylic acids producing an enhancing effect.
* This investigation was aided by grants from the Josiah Macy, Jr. Foundation, New York, and from the National Danish Association against Rheumatic Diseases.
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References
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