Download PDF
Thromb Haemost 1963; 10(02): 494-501
DOI: 10.1055/s-0038-1654799
Originalarbeiten — Original Article — Travaux Originaux
Schattauer GmbH

Haemophilia in the Dog Treatment with Heterologous Anti-Haemophilic Globulin

A. A Sharp
*   The Radcliffe Infirmary, Oxford
,
G. W. R Dike
**   The Medical Research Council Blood Coagulation Research Unit, Oxford
› Author Affiliations
Further Information

Publication History

Publication Date:
22 June 2018 (online)

Also available at
    Permissions and Reprints

Summary

The management of haemophilia in the dog is described in the light of the planned breeding of 10 litters of dogs from known carrier bitches.

The type and incidence of spontaneous haemorrhages, and the methods and effect of treatment with Antihaemophilic globulin concentrates prepared from bovine and pig blood are discussed.

This study has demonstrated that second and subsequent courses of these animal concentrates of AHG can produce effective levels in the blood and are not accompanied by a high incidence of reactions.

 

  • References

  • 1 Biggs R, Eveling J, Richards G. The assay of antihaemophilic globulin activity. Brit. J. Haemat. 01: 20 1962;
    PubMedSearch in Google Scholar
  • 2 Biggs R, Macfarlane R. G. Human blood coagulation and its disorders. Blackwell Scientific Publications. Oxford; 1962
    Search in Google Scholar
  • 3 Field R. A, Rickard C. G, Hutt F. B. Haemophilia in a family of dogs. Cornell Vet. 36: 285 1946;
    PubMedSearch in Google Scholar
  • 4 Graham J. B, Buckwater J. A, Hartley L. J, Brinkhous K. M. Canine haemophilia — Observations on the course, the clotting anomaly and the effect of blood Transfusions. J. exp. Med. 90: 97 1949;
    CrossrefPubMedSearch in Google Scholar
  • 5 Ouchterlony O. Progress in Allergy. Ed. Kallos P. Vol. V Karger; Basel: 1949
    Search in Google Scholar