A Congenital Inhibitor against Factor IX

H STOCKER

doi:10.1055/s-0038-1654874

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1965; 14(03/04): 346-360
DOI: 10.1055/s-0038-1654874

Originalarbeiten — Original Articles — Travaux Originaux

Schattauer GmbH

A Congenital Inhibitor against Factor IX

H STOCKER

¹Department of Internal Medicine, University of Basle (Head: Prof. Dr. F. Koller) (Work instructed by Dr. F.Duckert)

› Author Affiliations

Abstract

Summary

A new congenital hemorrhagic diathesis, which is due to the presence of a circulating inhibitor against factor IX, simulating a hemophilia B, is described. It is demonstrated, that the inhibitor becomes much less efficient when the factor VUI-concentration decreases. A hypothesis is given which should explain the role of factor VIII in the inhibition process.

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References

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