Thromb Haemost 1961; 05(03): 553-558
DOI: 10.1055/s-0038-1654948
Originalarbeiten – Original Article – Travaux Originaux
Schattauer GmbH

Influence of Erythrocytes and Calcium on Destruction of Platelets and on their Resin Affinity

R Honorato
1   Laboratorio de Quimica y Quimica Fisiológica, Escuela Dental Universidad de Chile
,
R Vásquez
1   Laboratorio de Quimica y Quimica Fisiológica, Escuela Dental Universidad de Chile
,
G Schindler
1   Laboratorio de Quimica y Quimica Fisiológica, Escuela Dental Universidad de Chile
› Author Affiliations
Further Information

Publication History

Publication Date:
21 June 2018 (online)

Summary

1. Destruction of platelets by glass and fixation of platelets by Amberlite IR 100 was studied.

2. A clear difference was established between platelets in whole blood, without anticoagulant and platelets in native plasma. Almost no platelets were destroyed or retained when in native plasma.

3. Male platelets in native plasma were clearly more resistant than female platelets in native plasma.

4. Differences were observed at different periods of the menstrual cycle.

5. Native male plasmas, very rich in platelets did not change in number after contact with glass or after passage through Amberlite IR 100. Thus calcium influenced neither destruction, nor fixation of platelets by resin.

 
  • Literatur

  • 1 Maupin B. Les plaquettes sanguines de l’homme. Masson et Cie. Paris: 1954
  • 2 Tocantins L. M. The Mammalian Blood Platelet in Health and Disease. Medicine (Baltimore) 17: 155 1938;
  • 3 Tocantins L. M. Historical Notes on Blood Platelets. Blood 03: 1075 1948;
  • 4 Quick A. J. Hemorrhagic Diseases. Lea and Febiger; Philadelphia: 1957
  • 5 Wright H. P. Characteristics of Blood Platelets. Their significance in Thrombus Formation. Blood Clotting and allied Problems. 119 Trans. 4th Conf. N. Y., Josiah Macy, Jr. Foundation, New York: 1951
  • 6 Honorato C. R, Schindler S. G. Influence of decalcifying agents in in increasing concentrations on stability of human platelets. This same Journal..
  • 7 Freeman G. Method for Obtaining Large Yields of Human Platelets as a By-Product of Blood Collection. Science 114: 527 1951;
  • 8 Honorato C. R, Vasquez T. R, Schindler S. G, Velasco A. Influence of red cells and of calcium on the resistance of Platelets and bn their affinity to a cation-exchange resin. Proc. Soc. de Biol, de Santiago, Chile. Abst. in Acta physiol, lat.-amer. 06: 43 1956;
  • 9 Cohn E. J. Blood Cells and Plasma Proteins. Academic Press; New York: 3-58 1953
  • 10 Honorato C. R, Vasquez T. R. Algunas caracteristicas de las plaquetas en relacion con el sexo. Asoc. Latino Am. de Cienc. Fisiol. 1° Reunion Cientifica, Punta del Este Uruguay 103 1957;