Fibrinolysis in the Pleural Cavity After Pulmonary Resection

C. L Zaman

doi:10.1055/s-0038-1654975

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1963; 09(01): 211-218
DOI: 10.1055/s-0038-1654975

Originalarbeiten — Original Articles — Travaux Originaux

Schattauer GmbH

Fibrinolysis in the Pleural Cavity After Pulmonary Resection

C. L Zaman M.D

¹Sanatorium “Berg en Bosch” Bilthoven and from the Clotting Derpartment of the Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam, The Netherlands

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Abstract

Summary

In the postoperative intrathoracic exsudate after pulmonary surgery a fluctuating antithrombin activity was found. The antithrombin in the exsudate was found to be mostly of a slow acting type. It differed from antithrombin III in its resistance to ether. The activity of the antithrombin in the exsudate could be potentiated by traces of heparin. For various reasons the hypothesis is brought forward that this antithrombin is a product of fibrinolysis. The effect of this antithrombin on haemostasis could not be evaluated. The haemostasis at the operation site was found to be influenced by fibrinolysis.

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References

References
1 Kowarzyk H, Siwinska-Kotschy M, Glogowska I, Czerwinska B. O antytrombinowym produkcie fibrynogenolizy i fibrynolizy. Postçpy Hig. Med. dos w. 12: 303 1958;
2 Lasch H. G. Über die Hemmung von Antithrombin durch Faktor VII. Dtsch. Arch, klin. Med. 201: 671 1955;
3 Niewiarowski S, Kowalski E. Un nouvel anticoagulant dérivé du fibrinogène. Rev. Hémat. 13: 320 1958;
4 Sokal G. Die Bestimmung der Antithrombinaktivitäten des Plasmas. Acta haemat. (Basel.) 14: 34 1955;
5 Stormorken H. Reactivity of stored plasma to thrombin, with reference to the fibrinogen conversion accelerator and heparinoid activity. Brit. J. Haemat. 03: 299 1957;
6 Triantaphyllopoulos D. C. Nature of the thrombin-inhibiting effect of incubated fibrinogen. Amer. J. Physiol. 197: 575 1959;
7 Zaman C. L. Fibrinolysis na longresectie. Thesis, Amsterdam. 1961