Idiopathische thrombozytopenische Purpura (Morbus Werlhof)

M. Winkelmann; R. E. Scharf; W. Schneider

doi:10.1055/s-0038-1655131

Hämostaseologie, Table of Contents

Hamostaseologie 1986; 06(01): 1-8
DOI: 10.1055/s-0038-1655131

Originalarbeiten

Schattauer GmbH

Idiopathische thrombozytopenische Purpura (Morbus Werlhof)

Pathogenese - Klinik - Verlauf

M. Winkelmann

¹Medizinische Universitätsklinik Düsseldorf, Abteilung für Hämatologie, Onkologie und klinische Immunologie

,

R. E. Scharf

¹Medizinische Universitätsklinik Düsseldorf, Abteilung für Hämatologie, Onkologie und klinische Immunologie

,

W. Schneider

¹Medizinische Universitätsklinik Düsseldorf, Abteilung für Hämatologie, Onkologie und klinische Immunologie

› Author Affiliations

Abstract

Zusammenfassung

Wir bevorzugen folgendes therapeutisches Vorgehen: Bei Patienten mit gesicherter ITP ist ein Abwarten gerechtfertigt, solange die Thrombozytenwerte mehr als 30000/µl betragen und keine manifesten Blutungen bestehen. Bei Thrombozyten werten unter 30000/µ1 sowie manifesten Blutungen beginnen wir eine PrednisolonTherapie mit initial mindestens 100 mg Prednisolon/die, gefolgt von einer ausschleichenden Dosierung über 6-8 Wochen nach Eintritt der Remission. Beim ersten Rezidiv wird individuell unterschiedlich entweder ein zweiter Therapieversuch mit Prednisolon unternommen oder eine Splenektomie durchgeführt.

Full Text

References

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