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Thromb Haemost 1966; 16(01/02): 302-310
DOI: 10.1055/s-0038-1655564
Originalarbeiten — Original Articles — Travaux Originaux
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Distribution, Half Life Time and Placental Transfer of the Protease Inhibitor Trasylol

F. K Beller M. D.   *)
1   Department of Obstetrics and Gynecology, New York University School of Medicine
,
M. D Epstein M. D.   **)
1   Department of Obstetrics and Gynecology, New York University School of Medicine
,
H Kaller   ***)
1   Department of Obstetrics and Gynecology, New York University School of Medicine
› Author AffiliationsThis work was aided by a grant from the National Institute of Child Healt and Human Development HD 00270-05.
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Publication Date:
26 June 2018 (online)

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Summary

A method is described for an assay of Trasylol in the circulation. By this method it was found that Trasylol disappears rapidly from the circulation. The half life time of elimination is approximately 150 minutes. The placental barrier is not crossed by this substance.

*) Career Scientist of the Health Research Council of the City of New York under contract I 297.


**) NIH Research Trainee under contract 5-TI-HD-l 1-05.


***) Privatdozent für Pharmakologie, University of Göttingen.


 

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