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Thromb Haemost 1964; 12(01): 119-125
DOI: 10.1055/s-0038-1655579
Originalarbeiten – Original Articles – Travaux Originaux
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The Plasmin Inhibitors of Plasma

I. A Method for their Estimation
Y Shamash   *)
1   The Marcus Memorial Blood Institute, Magen David Adom in Israel and Tel Aviv University, Tel Aviv, Isreal
,
A Rimon
1   The Marcus Memorial Blood Institute, Magen David Adom in Israel and Tel Aviv University, Tel Aviv, Isreal
› Author Affiliations
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Publication History

Publication Date:
24 July 2018 (online)

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Summary

A new method for the assay of plasmin inhibitors in human plasma is described. The method consists of determination of the caseinolytic activity of a standard plasmin solution before and after incubation with the inhibitor, with lysine added to the mixture as a stabilizer of plasmin. Using this method, it was found that plasma contains enough inhibitors to inactivate 30 caseinolytic units of plasmin, or 10 times the normal amount of plasminogen in human plasma.

*) This work is a part of a Ph. D. thesis to be submitted to the Senate of the Hebrew University, Jerusalem, Israel.


 

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