Download PDF
Schlaf 2018; 07(02): 85-89
DOI: 10.1055/s-0038-1660949
Review/Original
Schattauer GmbH

Zentrale Schlafapnoe: Freund oder Feind der Herzinsuffizienz?

Jens Spiesshoefer
Further Information

Publication History

Publication Date:
07 June 2018 (online)

    Permissions and Reprints

Die Pathophysiologie der zentralen Schlafapnoe (CSA) unterscheidet sich erheblich von der der obstruktiven Schlafapnoe (OSA). Im Gegensatz zur OSA kommt es bei der CSA zu zentral bedingten Atemaussetzern ohne eine entsprechende kompensatorische Atemanstrengung in Reaktion darauf (1,2).

 

  • Literatur

  • 1 Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Davidson SLWard, Tangredi MM. American Academy of Sleep M.. Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med 2012; 08 (05) 597-619.
    Search in Google Scholar
  • 2 Oldenburg O. Cheyne-stokes respiration in chronic heart failure. Treatment with adaptive servoventilation therapy. Circ J 2012; 76 (10) 2305-17.
    CrossrefPubMedSearch in Google Scholar
  • 3 Bitter T, Faber L, Hering D, Langer C, Horstkotte D, Oldenburg O. Sleep-disordered breathing in heart failure with normal left ventricular ejection fraction. Eur J Heart Fail 2009; 11 (06) 602-8.
    CrossrefPubMedSearch in Google Scholar
  • 4 Oldenburg O, Lamp B, Faber L, Teschler H, Horstkotte D, Topfer V. Sleep-disordered breathing in patients with symptomatic heart failure: a contemporary study of prevalence in and characteristics of 700 patients. Eur J Heart Fail 2007; 09 (03) 251-7.
    CrossrefPubMedSearch in Google Scholar
  • 5 Lorenzi-Filho G, Dajani HR, Leung RS, Floras JS, Bradley TD. Entrainment of blood pressure and heart rate oscillations by periodic breathing. Am J Respir Crit Care Med 1999; 159 (4 Pt 1): 1147-54.
    CrossrefPubMedSearch in Google Scholar
  • 6 Bradley TD, Floras JS. Sleep apnea and heart failure: Part II: central sleep apnea. Circulation 2003; 107 (13) 1822-6.
    CrossrefPubMedSearch in Google Scholar
  • 7 Wedewardt J, Bitter T, Prinz C, Faber L, Horstkotte D, Oldenburg O. Cheyne-Stokes respiration in heart failure: cycle length is dependent on left ventricular ejection fraction. Sleep Med 2010; 11 (02) 137-42.
    CrossrefPubMedSearch in Google Scholar
  • 8 Tkacova R, Niroumand M, Lorenzi-Filho G, Bradley TD. Overnight shift from obstructive to central apneas in patients with heart failure: role of PCO2 and circulatory delay. Circulation 2001; 103 (02) 238-43.
    CrossrefPubMedSearch in Google Scholar
  • 9 Solin P, Bergin P, Richardson M, Kaye DM, Walters EH, Naughton MT. Influence of pulmonary capillary wedge pressure on central apnea in heart failure. Circulation 1999; 99 (12) 1574-9.
    CrossrefPubMedSearch in Google Scholar
  • 10 Andreas S, Schulz R, Werner GS, Kreuzer H. Prevalence of obstructive sleep apnoea in patients with coronary artery disease. Coron Artery Dis 1996; 07 (07) 541-5.
    CrossrefSearch in Google Scholar
  • 11 Cowie MR, Woehrle H, Wegscheider K, Angermann C, d’Ortho MP, Erdmann E, Levy P, Simonds AK, Somers VK, Zannad F, Teschler H. Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure. N Engl J Med 2015; 373 (12) 1095-105.
    CrossrefPubMedSearch in Google Scholar
  • 12 Naughton MT. Cheyne-Stokes respiration: friend or foe?. Thorax 2012; 67 (04) 357-60.
    CrossrefPubMedSearch in Google Scholar
  • 13 Hu K, Li Q, Yang J, Hu S, Chen X. The effect of theophylline on sleep-disordered breathing in patients with stable chronic congestive heart failure. Chin Med J (Engl) 2003; 116 (11) 1711-6.
    Search in Google Scholar
  • 14 Javaheri S. Acetazolamide improves central sleep apnea in heart failure: a double-blind, prospective study. Am J Respir Crit Care Med 2006; 173 (02) 234-7.
    CrossrefPubMedSearch in Google Scholar
  • 15 Javaheri S, Parker TJ, Wexler L, Liming JD, Lindower P, Roselle GA. Effect of theophylline on sleep-disordered breathing in heart failure. N Engl J Med 1996; 335 (08) 562-7.
    CrossrefPubMedSearch in Google Scholar
  • 16 Andreas S, Weidel K, Hagenah G, Heindl S. Treatment of Cheyne-Stokes respiration with nasal oxygen and carbon dioxide. Eur Respir J 1998; 12 (02) 414-9.
    CrossrefPubMedSearch in Google Scholar
  • 17 Franklin KA, Eriksson P, Sahlin C, Lundgren R. Reversal of central sleep apnea with oxygen. Chest 1997; 111 (01) 163-9.
    CrossrefPubMedSearch in Google Scholar
  • 18 Sasayama S, Izumi T, Seino Y, Ueshima K, Asanoi H, Group C-HS. Effects of nocturnal oxygen therapy on outcome measures in patients with chronic heart failure and cheyne-stokes respiration. Circ J 2006; 70 (01) 1-7.
    CrossrefPubMedSearch in Google Scholar
  • 19 Mebrate Y, Willson K, Manisty CH, Baruah R, Mayet J, Hughes AD, Parker KH, Francis DP. Dynamic CO2 therapy in periodic breathing: a modeling study to determine optimal timing and dosage regimes. J Appl Physiol (1985) 2009; 107 (03) 696-706.
    CrossrefPubMedSearch in Google Scholar
  • 20 Szollosi I, Jones M, Morrell MJ, Helfet K, Coats AJ, Simonds AK. Effect of CO2 inhalation on central sleep apnea and arousals from sleep. Respiration 2004; 71 (05) 493-8.
    CrossrefPubMedSearch in Google Scholar
  • 21 Wan ZH, Wen FJ, Hu K. Dynamic CO(2) inhalation: a novel treatment for CSR-CSA associated with CHF. Sleep Breath 2013; 17 (02) 487-93.
    CrossrefPubMedSearch in Google Scholar
  • 22 Bradley TD, Logan AG, Kimoff RJ, Series F, Morrison D, Ferguson K, Belenkie I, Pfeifer M, Fleetham J, Hanly P, Smilovitch M, Tomlinson G, Floras JS, Investigators C. Continuous positive airway pressure for central sleep apnea and heart failure. N Engl J Med 2005; 353 (19) 2025-33.
    CrossrefPubMedSearch in Google Scholar
  • 23 Arzt M, Floras JS, Logan AG, Kimoff RJ, Series F, Morrison D, Ferguson K, Belenkie I, Pfeifer M, Fleetham J, Hanly P, Smilovitch M, Ryan C, Tomlinson G, Bradley TD. Suppression of central sleep apnea by continuous positive airway pressure and transplant-free survival in heart failure: a post hoc analysis of the Canadian Continuous Positive Airway Pressure for Patients with Central Sleep Apnea and Heart Failure Trial (CANPAP). Circulation 2007; 115 (25) 3173-80.
    CrossrefPubMedSearch in Google Scholar
  • 24 Kasai T, Usui Y, Yoshioka T, Yanagisawa N, Takata Y, Narui K, Yamaguchi T, Yamashina A, Momomura SI, Investigators J. Effect of flow-triggered adaptive servo-ventilation compared with continuous positive airway pressure in patients with chronic heart failure with coexisting obstructive sleep apnea and Cheyne-Stokes respiration. Circ Heart Fail 2010; 03 (01) 140-8.
    CrossrefPubMedSearch in Google Scholar
  • 25 Philippe C, Stoica-Herman M, Drouot X, Raffestin B, Escourrou P, Hittinger L, Michel PL, Rouault S, d’Ortho MP. Compliance with and effectiveness of adaptive servoventilation versus continuous positive airway pressure in the treatment of Cheyne-Stokes respiration in heart failure over a six month period. Heart 2006; 92 (03) 337-42.
    Search in Google Scholar
  • 26 Teschler H, Dohring J, Wang YM, Berthon-Jones M. Adaptive pressure support servo-ventilation: a novel treatment for Cheyne-Stokes respiration in heart failure. Am J Respir Crit Care Med 2001; 164 (04) 614-9.
    CrossrefPubMedSearch in Google Scholar
  • 27 Cowie MR, Woehrle H, Wegscheider K, Angermann C, d’Ortho MP, Erdmann E, Levy P, Simonds A, Somers VK, Zannad F, Teschler H. Rationale and design of the SERVEHF study: treatment of sleep-disordered breathing with predominant central sleep apnoea with adaptive servoventilation in patients with chronic heart failure. Eur J Heart Fail 2013; 15 (08) 937-43.
    CrossrefPubMedSearch in Google Scholar
  • 28 Damy T, Margarit L, Noroc A, Bodez D, Guendouz S, Boyer L, Drouot X, Lamine A, Paulino A, Rappeneau S, Stoica MH, Dubois-Rande JL, Adnot S, Hittinger L, d’Ortho MP. Prognostic impact of sleep-disordered breathing and its treatment with nocturnal ventilation for chronic heart failure. Eur J Heart Fail 2012; 14 (09) 1009-19 91 aus Book.
    CrossrefPubMedSearch in Google Scholar
  • 29 Oldenburg O, Bitter T, Vogt J, Fischbach T, Dimitriadis Z, Bullert K, Horstkotte D. Central and obstructive sleep apnea are associated with increased mortality in patients with long-term cardiac resynchronization therapy. J Am Coll Cardiol 2011; 54 (Suppl. A) E100 93 aus Book.
    Search in Google Scholar
  • 30 Wu X, Fu C, Zhang S, Liu Z, Li S, Jiang L. Adaptive servoventilation improves cardiac dysfunction and prognosis in heart failure patients with sleep-disordered breathing: a meta-analysis. Clin Respir J. 2015
    PubMedSearch in Google Scholar
  • 31 Philip-Joet FF, Paganelli FF, Dutau HL, Saadjian AY. Hemodynamic effects of bilevel nasal positive airway pressure ventilation in patients with heart failure. Respiration 1999; 66 (02) 136-43.
    CrossrefPubMedSearch in Google Scholar
  • 32 Miyata M, Yoshihisa A, Suzuki S, Yamada S, Kamioka M, Kamiyama Y, Yamaki T, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y. Adaptive servo ventilation improves Cheyne-Stokes respiration, cardiac function, and prognosis in chronic heart failure patients with cardiac resynchronization therapy. J Cardiol 2012; 60 (03) 222-7.
    CrossrefPubMedSearch in Google Scholar
  • 33 Hetland A, Haugaa KH, Olseng M, Gjesdal O, Ross S, Saberniak J, Jacobsen MB, Edvardsen T. Three-month treatment with adaptive servoventilation improves cardiac function and physical activity in patients with chronic heart failure and cheyne-stokes respiration: a prospective randomized controlled trial. Cardiology 2013; 126 (02) 81-90.
    CrossrefPubMedSearch in Google Scholar
  • 34 Momomura S, Seino Y, Kihara Y, Adachi H, Yasumura Y, Yokoyama H, Wada H, Ise T, Tanaka K, investigators S-C. Adaptive servo-ventilation therapy for patients with chronic heart failure in a confirmatory, multicenter, randomized, controlled study. Circ J 2015; 79 (05) 981-90.
    CrossrefPubMedSearch in Google Scholar