Introduction:
Non-selective unilateral laryngeal reinnervation (ULR) is the surgical anastomosis
between the recurrent laryngeal nerve (RLN) with a motor nerve in unilateral vocal
fold paralysis (UVP). We present the results of nine patients in whom non-selective
ULR was performed as salvage treatment after unsuccessful thyroplasty.
Methods:
Nine patients with UVP and persistent dysphonia after thyroplasty were included in
this prospective, unicentric study. Reinnervation was achieved by surgical anastomosis
between the RLN and the ansa cervicalis. Voice quality was measured by use of a questionnaire
(Rouen Voice Questionnaire: 0 – 140), phoniatric voice evaluation (GRBAS-Scale, Hirano)
and computer assisted voice analysis (shimmer, jitter, maximal phonation time in seconds,
maximal intensity in dB) pre- and postoperative after 1 – 3, 12 or more months (m).
Results:
We observed significant improvement of self-evaluated voice quality measured by questionnaire
(pre: 91.83, 1 – 3 m: 52, 36 m: 24 (p < 0.001)). Computerized phonation parameters
significantly improved over time (jitter: pre: 3.25, 1 – 3 m: 1,49, 12 m: 1.14 (p
=.01); shimmer: pre: 1.29, 1 – 3 m: 0.68, 12 m: 0.49 (p < .017). Maximal voice intensity
significantly improved over time (max. intensity (dB): pre: 90.85 1 – 3 m: 91.1, 12
m: 96.4 (p < .012)). No significant improvement of maximal phonation time over time
was observed (max. phonation time (s): pre: 8.77, 1 – 3 m: 8.9; 12 m: 12.88 p = 0.65).
A significant improvement of externally assessed voice quality measured by the Hirano-score
was observed.
Conclusions:
Non-selective ULR in UVP is a reliable and stable therapeutic option as salvage treatment
for patients with persistent dysphonia after unsuccessful thyroplasty.