CC BY-NC-ND 4.0 · Laryngorhinootologie 2019; 98(S 02): S65-S66
DOI: 10.1055/s-0039-1685959
Abstracts
Oncology

Prognostic significance of perioperative blood transfusions in head and neck squamous cell carcinoma

P Baumeister
1   Klinikum Großhadern, München
,
M Reiter
1   Klinikum Großhadern, München
,
M Canis
1   Klinikum Großhadern, München
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    Aim:

    To evaluate the prognostic impact of perioperative blood transfusions (PBT) for patients with head and neck squamous cell carinomas (HNSCC).

    Method:

    Retrospective analysis of survival of 354 HNSCC patients primarily treated with surgery with regard to preoperative anemia and PBT.

    Results:

    Patients who received PBT showed a reduced overall survival. An increase of cancer recurrences was not observed. PBT was needed more frequently by older patients in worse physical conditions and with advanced stage carcinomas. Subgroup analyses revealed, however, a comparable effect for younger patients, patients with p16-positive HNSCC and earyl stage cancers.

    Conclusion:

    Despite again confirmed, profoundly negative effects of preoperative anemia on disease free and overall survival we suggest a restrictive transfusion policy whenever possible.


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    Priv.-Doz. Dr. med. Philipp Baumeister
    Klinikum Großhadern,
    Marchioninistr. 15, 81377
    München

    Publikationsverlauf

    Publikationsdatum:
    23. April 2019 (online)

    © 2019. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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