Herein, we describe a simple synthetic strategy to assemble aza-polyquinane systems containing an indole motif by employing the Fischer indolization and ring-rearrangement metathesis as key steps. The precursor used here is exo-dicyclopentadienone, which is derived from less explored exo-dicyclopentadiene. By using this approach, several aza-polyquinanes that contain indole units and fused medium rings (eight- and nine-membered rings) were synthesized in good yields.
Key words
exo-dicyclopentadiene - Fischer indolization - ring-rearrangement metathesis - aza-polyquinane - medium rings - polycyclic
