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Synlett 2020; 31(06): 615-621
DOI: 10.1055/s-0039-1690781
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© Georg Thieme Verlag Stuttgart · New York

Synthesis of Novel 1,2,3-Triazole-Dihydropyrimidinone Hybrids Using Multicomponent 1,3-Dipolar Cycloaddition (Click)–Biginelli Reactions: Anticancer Activity

a   Centro de Química de Évora & LAQV-Requimte, University of Évora, Institute for Research and Advanced Training (IIFA), Rua Romão Ramalho, 59, 7000-671 Évora, Portugal   Email: betepc@uevora.pt   Email: bete_carreiro@yahoo.com
,
Ana M. Sena
b   Department of Chemistry, University of Évora, School of Science and Technology, Rua Romão Ramalho, 59, 7000-671 Évora, Portugal
,
Adrián Puerta
c   BioLab, Instituto Universitario de Bio-Orgánica ‘Antonio González’, Universidad de La Laguna, PO Box 456, 38200 La Laguna, Islas Canarias, Spain
,
José M. Padrón
c   BioLab, Instituto Universitario de Bio-Orgánica ‘Antonio González’, Universidad de La Laguna, PO Box 456, 38200 La Laguna, Islas Canarias, Spain
,
a   Centro de Química de Évora & LAQV-Requimte, University of Évora, Institute for Research and Advanced Training (IIFA), Rua Romão Ramalho, 59, 7000-671 Évora, Portugal   Email: betepc@uevora.pt   Email: bete_carreiro@yahoo.com
b   Department of Chemistry, University of Évora, School of Science and Technology, Rua Romão Ramalho, 59, 7000-671 Évora, Portugal
› Author Affiliations

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