Download PDF
J Pediatr Intensive Care 2020; 09(01): 051-053
DOI: 10.1055/s-0039-1696652
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Confirmation of Brain Death with Positron Emission Tomography

Semra Ozdemir
1   Department of Nuclear Medicine, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey
,
Yusuf Ziya Tan
1   Department of Nuclear Medicine, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey
,
Fulya Koc Ozturk
1   Department of Nuclear Medicine, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey
,
Fatih Battal
2   Department of Pediatrics, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey
› Author Affiliations Funding None declared.
Further Information

Publication History

19 May 2019

25 July 2019

Publication Date:
06 September 2019 (online)

Also available at
    Permissions and Reprints

Abstract

After recent advances regarding organ transplantation, accurate and timely diagnosis of brain death has gained importance. In the diagnosis of brain death, in addition to clinical findings, various ancillary tests are very crucial. In this study, the scintigraphic imaging of the brain death of an 8-year-old girl with both Tc-99m diethylenetriaminepentaacetic and 18F-fluorodeoxyglucose (FDG) has been presented. This case study shows that 18F-FDG positron emission tomography-computed tomography imaging can be a useful technique in evaluating brain death in patients.

Keywords

brain death - diethylenetriaminepentaacetic acid - F-18 fluorodeoxyglucose

Authors' Contributions

All authors contributed equally to this work, read, and approved the final manuscript.


 

  • References

  • 1 Oderberg DS. Death, unity, and the brain. Theor Med Bioeth 2019; 40 (05) 359-379
    CrossrefPubMedGoogle Scholar
  • 2 Wilson K, Gordon L, Selby Sr JB. The diagnosis of brain death with Tc-99m HMPAO. Clin Nucl Med 1993; 18 (05) 428-434
    CrossrefPubMedGoogle Scholar
  • 3 Sinha P, Conrad GR. Scintigraphic confirmation of brain death. Semin Nucl Med 2012; 42 (01) 27-32
    CrossrefPubMedGoogle Scholar
  • 4 Kirschen MP, Francoeur C, Murphy M. , et al. Epidemiology of brain death in pediatric intensive care units in the United States. JAMA Pediatr 2019; 173 (05) 469-476
    CrossrefPubMedGoogle Scholar
  • 5 Li Y, Liu S, Xun F, Liu Z, Huang X. Use of transcranial doppler ultrasound for diagnosis of brain death in patients with severe cerebral injury. Med Sci Monit 2016; 22: 1910-1915
    CrossrefPubMedGoogle Scholar
  • 6 Shewmon DA. False-positive diagnosis of brain death following the pediatric guidelines: case report and discussion. J Child Neurol 2017; 32 (14) 1104-1117
    CrossrefPubMedGoogle Scholar
  • 7 Spieth ME, Ansari AN, Kawada TK, Kimura RL, Siegel ME. Direct comparison of Tc-99m DTPA and Tc-99m HMPAO for evaluating brain death. Clin Nucl Med 1994; 19 (10) 867-872
    CrossrefPubMedGoogle Scholar
  • 8 Meyer MA. Evaluating brain death with positron emission tomography: case report on dynamic imaging of 18F-fluorodeoxyglucose activity after intravenous bolus injection. J Neuroimaging 1996; 6 (02) 117-119
    CrossrefPubMedGoogle Scholar