In vitro antioxidant activity of Modern Botany™ products and selected natural product ingredients

The project aim was to investigate antioxidant activity of selected Modern Botany™ products and their ingredients. Modern Botany™ oil from different manufacturing sources was tested for antioxidant activity and results showed, compared to the control Tocopherol (Vit E) a known antioxidant that the Irish manufactured Modern Botany Oil exhibited 80 % DPPH radical scavenging activity, compared to UK manufactured product which had a DPPH of 73 %. Selected ingredients such as Borago officinalis (Borage), Calendula officinalis (Marigold), and Linum usitassimum (Flaxseed) ([table 1] [1] [2], also exhibited significant antioxidant activity and would warrant further analysis. These tests of Modern Botany™ products suggest that further testing is warranted for antimicrobial and antioxidant activity.

Tab. 1

% DPPH scavenging and Trolox equivalence (mM) for Modern Botany Oil & Selected Ingredients

	Average ABS (Con)	Average Abs (Sam)	StdDev (Sample)	%DPPH (0.05mM)	Trolox equivalent (mM)
Tocopherol(control)	0.544	0.086	0.020	84	1.61
MB(IE) Oil (new)	0.544	0.111	0.003	80	1.45
MB(IE) Oil (old)	0.544	0.118	0.004	78	1.40
MB UK Oil	0.544	0.147	0.025	73	1.22
Borage (IE)	0.544	0.186	0.016	66	0.96
Calendula	0.544	0.196	0.030	64	0.90
Flax(UK)	0.544	0.25	0.086	54	0.54
Flax(IE)	0.544	0.297	0.090	45	0.24
Borage (UK)	0.544	0.395	0.033	27	-0.40
Rosewood	0.544	0.453	0.065	17	-0.79
Chamomile	0.544	0.486	0.038	11	-1.0

• References

• 1 Heinrich M, Kinghorn A, Phillipson J, Maizels D, Gibbons S. Fundamentals of Pharmacogosy and Phytotherapy. Second. Ed. Ch4. Edinburgh: Elsevier; 2012: 33-48
• 2 Gupta M. Singh. Borago officinalis An important medicinal plant of Mediterranean region: Review. Int J Pharm Sci Rev Res 2010; 5 (I): 27-34