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DOI: 10.1055/s-0039-3403313
Invasive mediastinal aspergillosis with tracheal perforation in a patient with acute myeloid leukemia
Publication History
Publication Date:
28 February 2020 (online)
Pulmonary aspergillosis is a life-threatening complication in immunocompromised patients. It is an opportunistic disease, which predominantly occurs in the lungs, although dissemination to virtually any organ is possible.
We report a case of a 35 year old male with newly diagnosed acute myeloid leukemia who presented with a right lateral perforation of the trachea due to invasive aspergillosis infection. Initially bronchoscopic stenting was performed with initiation of an antimycotic therapy which consisted of liposomal Amphotericin B and Caspofungin. Due to a rather large tracheal mycotic perforation the indication for surgical treatment was given in order to allow the start of a timely highdose chemotherapy.
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