ENDOSCOPIC RECURRENCE AFTER ILEOCAECAL RESECTION FOR CROHN´S DISEASE RELATING TO MICROSCOPIC INFLAMMATION AT RESECTION MARGINS

L Kunovsky; K Poredska; F Marek; Z Kala; V Prochazka; J Dolina; V Zboril; R Kroupa; J Vaculova; T Pavlik; J Vlazny; P Jabandziev; D Ivanecka; L Mitas

doi:10.1055/s-0040-1704693

Endoscopy, Table of Contents

Endoscopy 2020; 52(S 01): S222
DOI: 10.1055/s-0040-1704693

ESGE Days 2020 ePoster Podium presentations

Saturday, April 25, 2020 11:30 – 12:00 IBD 3 ePoster Podium 5

ENDOSCOPIC RECURRENCE AFTER ILEOCAECAL RESECTION FOR CROHN´S DISEASE RELATING TO MICROSCOPIC INFLAMMATION AT RESECTION MARGINS

L Kunovsky

¹Masaryk University, Department of Gastroenterology, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

²Masaryk University, Department of Surgery, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

,

K Poredska

¹Masaryk University, Department of Gastroenterology, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

,

F Marek

²Masaryk University, Department of Surgery, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

,

Z Kala

²Masaryk University, Department of Surgery, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

,

V Prochazka

²Masaryk University, Department of Surgery, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

,

J Dolina

¹Masaryk University, Department of Gastroenterology, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

,

V Zboril

¹Masaryk University, Department of Gastroenterology, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

,

R Kroupa

¹Masaryk University, Department of Gastroenterology, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

,

J Vaculova

¹Masaryk University, Department of Gastroenterology, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

,

T Pavlik

³Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic

,

J Vlazny

⁴Masaryk University, Department of Pathology, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

,

P Jabandziev

⁵Masaryk University, Department of Pediatrics, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

,

D Ivanecka

²Masaryk University, Department of Surgery, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

,

L Mitas

²Masaryk University, Department of Surgery, University Hospital Brno, Faculty of Medicine, Brno, Czech Republic

› Author Affiliations

Abstract

Full Text

Aims An early postoperative endoscopic recurrence of Crohn´s disease after ileocaecal resection remains unclear concerning its pathogenesis and risk factors. In our study, we evaluated the influence of histological inflammation at the resection margins on endoscopic recurrence.

Methods Patients with CD who underwent ileocaecal resection have been prospectively followed up in our study. The specimens were histologically analysed for inflammation at both of the resection margins (ileal and colonic). We evaluated whether histological results of the resection margins are correlated with endoscopic recurrence of CD based on colonoscopy 6 months after ileocaecal resection.

Results We have included 107 patients in our study. Six months after ileocaecal resection, 23 patients (21.5 %) had an endoscopic recurrence of CD. The histological signs of CD at the resection margins were associated with a higher endoscopic recurrence (56.5 % versus 4.8 %, p < 0.001).

Conclusions Microscopic inflammation at the resection margins was significantly associated with a higher risk of early postoperative endoscopic recurrence after an ileocaecal resection for CD.