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DOI: 10.1055/s-0040-1704866
DEVELOPMENT OF ENDOSCOPIC SCORING SYSTEM TO PREDICT RISK OF INTESTINAL TYPE GASTRIC CANCER: PRELIMINARY PROSPECTIVE STUDY
Publikationsverlauf
Publikationsdatum:
23. April 2020 (online)
Aims We aimed to develop endoscopic scoring system to evaluate atrophic gastritis and intestinal metaplasia using narrowing band imaging (NBI) and magnification view and to compare endoscopic scores with Operative link for gastritis assessment (OLGA) and Operative link for gastric intestinal metaplasia assessment (OLGIM).
Methods Total 28 patients underwent diagnostic esophagogastroduodenoscopy were enrolled and endoscopic scoring using NBI and magnification view were performed. Four areas (the lesser and greater curvatures of the antrum and the lesser and greater curvature side of the body) were observed and biopsies were taken. Degree of atrophy was scored from 0 to 2 according to Kimura-Takemoto classification (0: C0-2, 1: C3-O1, 2: O2-3). Degree of metaplasia was scored from 0 to 3 (0: no metaplasia, 1: metaplasia at antrum, 2: metaplasia at body, + 1: 1/2 > observed filed). Endoscopic scores were compared to OLGA and OLGIM staging.
Results Correlation coefficients for atrophy between endoscopic and histologic scores 0.85 (95% CI: 0.70–0.93, p < 0.001) and those for metaplasia was 0.74 (95% CI: 0.85–0.87; p < 0.001). For atrophic gastritis, endoscopic score > 1 correlated OLGA Stage III and IV with a sensitivity, specificity, positive predictive value, and negative predictive value of 92%, 88%, 86% and 93%, respectively and for metaplasia, endoscopic score > 1 correlated high OLGIM Stage III and IV with those values of 78%, 100%, 100% and 73%, respectively.
Conclusions Endoscopic scoring for gastric atrophy and intestinal metaplasia using NBI-magnification view seems to correlate well with histologic staging.
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