Synthesis 2020; 52(24): 3751-3763
DOI: 10.1055/s-0040-1707342
short review
© Georg Thieme Verlag Stuttgart · New York

Reductive Cross-Coupling of Vinyl Electrophiles

Xiaobo Pang
,
Xuejing Peng
,
State Key Laboratory of Applied Organic Chemistry (SKLAOC), College of Chemistry and Chemical Engineering, Lanzhou University, 222 South Tianshui Road, Lanzhou, 730000, China   Email: shuxingzh@lzu.edu.cn
› Author Affiliations
We thank the National Natural Science Foundation of China for their financial support (21772072, 21502078).
Further Information

Publication History

Received: 20 May 2020

Accepted after revision: 25 June 2020

Publication Date:
11 August 2020 (online)


Abstract

The synthesis of alkenes (olefins) is a central subject in the synthetic community. The transition-metal-catalyzed reductive cross-coupling of vinyl electrophiles has emerged as a promising tool to produce alkenes with improved flexibility, structural complexity, and functionality tolerance. In this review, we summarized the progress in this field with respect to cross-electrophile couplings and reductive Heck reactions using vinyl electrophiles.

1 Introduction

2 Cross-Electrophile Coupling of Vinyl Electrophiles

3 Reductive Heck Reaction of Vinyl Electrophiles

4 Summary and Outlook