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Semin Respir Crit Care Med 2020; 41(05): 652-658
DOI: 10.1055/s-0040-1713799
Review Article

Hepatic Sarcoidosis: Current Concepts and Treatments

Geoffrey Rossi
1   Service de Médecine Interne, Centre Hospitalier Universitaire Henri-Mondor, Assistance Publique—Hôpitaux de Paris, Université Paris Est Créteil, Créteil, France
,
Marianne Ziol
2   Service d'anatomopathologie, Centre Hospitalier Jean-Verdier, Bondy, France
,
Dominique Roulot
3   Service d'Hépatologie, Centre Hospitalier Universitaire Avicenne, Bobigny, France
4   Service de Pneumologie, Centre Hospitalier Universitaire Avicenne, Université Sorbonne Paris Nord, APHP, Bobigny, France
,
Dominique Valeyre
4   Service de Pneumologie, Centre Hospitalier Universitaire Avicenne, Université Sorbonne Paris Nord, APHP, Bobigny, France
,
Matthieu Mahévas
1   Service de Médecine Interne, Centre Hospitalier Universitaire Henri-Mondor, Assistance Publique—Hôpitaux de Paris, Université Paris Est Créteil, Créteil, France
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Abstract

Hepatic sarcoidosis is a relatively common manifestation of extrapulmonary sarcoidosis. It occurs in 20 to 30% of cases and is rarely severe. However, a cluster of patients may develop severe complications such as cirrhosis and portal hypertension. In this review, we describe the current knowledge of clinical, biological, pathological, and radiological features of liver involvement in sarcoidosis and discuss essential clues for management and treatment.

Keywords

sarcoidosis - hepatic sarcoidosis - liver - cholestasis - granulomas


Publication History

Article published online:
10 August 2020

© 2020. Thieme. All rights reserved.

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