Pediatric Metronidazole-Induced Encephalopathy: A Case Report and Review of the Literature

Alberto M. Cappellari; Donata Rossetti; Sabrina Avignone; Elisa Scola; Antonio Di Cesare

doi:10.1055/s-0040-1716347

Journal of Pediatric Neurology, Inhaltsverzeichnis

Journal of Pediatric Neurology 2021; 19(02): 136-142
DOI: 10.1055/s-0040-1716347

Case Report

Pediatric Metronidazole-Induced Encephalopathy: A Case Report and Review of the Literature

Alberto M. Cappellari

¹Department of Neuroscience, Fondazione Scientific Institute for Research, Hospitalization and Healthcare Cà Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

,

Donata Rossetti

²Department of Pediatrics, University of Milan, Milan, Italy

,

Sabrina Avignone

³Department of Neuroradiology, Fondazione Scientific Institute for Research, Hospitalization and Healthcare Cà Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

,

Elisa Scola

³Department of Neuroradiology, Fondazione Scientific Institute for Research, Hospitalization and Healthcare Cà Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

,

Antonio Di Cesare

⁴Department of Pediatric Surgery, Fondazione Scientific Institute for Research, Hospitalization and Healthcare Ca' Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

› Institutsangaben

Abstract

Metronidazole-induced encephalopathy is a rare toxic encephalopathy secondary to the common use to this antimicrobial drug. It has been reported mainly in adult patients but only rarely in children. Owing to possible devastating complication of this disease, clinicians should have a higher index of suspicion for encephalopathic patients on metronidazole therapy. Here, we report a 5-month-old infant with metronidazole-induced encephalopathy presenting with nonconvulsive status epilepticus. A review of the literature in pediatric, as well as adult metronidazole-induced encephalopathy, is also provided.

Keywords

metronidazole - encephalopathy - nonconvulsive status epilepticus

Volltext

Referenzen

References
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