Download PDF
J Neurol Surg A Cent Eur Neurosurg 2021; 82(06): 599-603
DOI: 10.1055/s-0040-1718693
Case Report

Differential Diagnosis of Central Neurocytoma: Two Cases

V.K Steinsiepe
1   Department of Neurosurgery, Kantonsspital St. Gallen, St. Gallen, Switzerland
,
H Frick
2   Institute of Pathology, Kantonsspital St. Gallen, St. Gallen, Switzerland
,
W Jochum
2   Institute of Pathology, Kantonsspital St. Gallen, St. Gallen, Switzerland
,
J.Y Fournier
3   Department of Neurosurgery, Hôpital de Sion, Sion, Switzerland
› Author Affiliations
› Further Information
Also available at
    Permissions and Reprints

Abstract

Central neurocytoma are rare primary brain tumors of the young and middle-aged adult, typically located in the lateral ventricles. Diagnosis has historically been difficult due to histomorphologic similarities to oligodendroglioma and ependymal tumors and remains a challenge even today. We present two cases of intraventricular central neurocytoma in which careful consideration of the clinical and radiological findings led to reevaluation of the preliminary histological interpretation, highlighting the importance of a meticulous differential diagnosis.

Keywords

neurocytoma - cerebral ventricle neoplasm - differential diagnosis - case report - immunohistochemistry

Patient Consent

The patients have consented to the submission of the case report to the journal.




Publication History

Received: 17 October 2019

Accepted: 20 December 2019

Article published online:
22 December 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • References

  • 1 Hassoun J, Gambarelli D, Grisoli F. et al. Central neurocytoma. An electron-microscopic study of two cases. Acta Neuropathol 1982; 56 (02) 151-156
    CrossrefPubMedGoogle Scholar
  • 2 Scheithauer BW. Development of the WHO classification of tumors of the central nervous system: a historical perspective. Brain Pathol 2009; 19 (04) 551-564
    CrossrefPubMedGoogle Scholar
  • 3 Kim DG, Chi JG, Park SH. et al. Intraventricular neurocytoma: clinicopathological analysis of seven cases. J Neurosurg 1992; 76 (05) 759-765
    CrossrefPubMedGoogle Scholar
  • 4 Maiuri F, Spaziante R, De Caro ML, Cappabianca P, Giamundo A, Iaconetta G. Central neurocytoma: clinico-pathological study of 5 cases and review of the literature. Clin Neurol Neurosurg 1995; 97 (03) 219-228
    CrossrefPubMedGoogle Scholar
  • 5 Yaşargil MG, von Ammon K, von Deimling A, Valavanis A, Wichmann W, Wiestler OD. Central neurocytoma: histopathological variants and therapeutic approaches. J Neurosurg 1992; 76 (01) 32-37
    CrossrefPubMedGoogle Scholar
  • 6 Qian H, Lin S, Zhang M, Cao Y. Surgical management of intraventricular central neurocytoma: 92 cases. Acta Neurochir (Wien) 2012; 154 (11) 1951-1960
    CrossrefPubMedGoogle Scholar
  • 7 Vasiljevic A, François P, Loundou A. et al. Prognostic factors in central neurocytomas: a multicenter study of 71 cases. Am J Surg Pathol 2012; 36 (02) 220-227
    CrossrefPubMedGoogle Scholar
  • 8 Chang KH, Han MH, Kim DG. et al. MR appearance of central neurocytoma. Acta Radiol 1993; 34 (05) 520-526
    CrossrefPubMedGoogle Scholar
  • 9 Wichmann W, Schubiger O, von Deimling A, Schenker C, Valavanis A. Neuroradiology of central neurocytoma. Neuroradiology 1991; 33 (02) 143-148
    CrossrefPubMedGoogle Scholar
  • 10 von Deimling A, Janzer R, Kleihues P, Wiestler OD. Patterns of differentiation in central neurocytoma. An immunohistochemical study of eleven biopsies. Acta Neuropathol 1990; 79 (05) 473-479
    CrossrefPubMedGoogle Scholar
  • 11 You H, Kim YI, Im SY. et al. Immunohistochemical study of central neurocytoma, subependymoma, and subependymal giant cell astrocytoma. J Neurooncol 2005; 74 (01) 1-8
    CrossrefPubMedGoogle Scholar
  • 12 Park HK, Steven D C. Stereotactic radiosurgery for central neurocytoma: a quantitative systematic review. J Neurooncol 2012; 108 (01) 115-121
    CrossrefPubMedGoogle Scholar
  • 13 Rades D, Schild SE. Treatment recommendations for the various subgroups of neurocytomas. J Neurooncol 2006; 77 (03) 305-309
    CrossrefPubMedGoogle Scholar
  • 14 Baroncini M, Peltier J, Le Gars D, Lejeune J-P. Tumeurs du ventricule latéral. Analyse d'une série de 284 cas. Neurochirurgie 2011; 57 (4–6): 170-179
    CrossrefPubMedGoogle Scholar
  • 15 Dănăilă L. Primary tumors of the lateral ventricles of the brain. Chirurgia (Bucur) 2013; 108 (05) 616-630
    PubMedGoogle Scholar
  • 16 Delfini R, Acqui M, Oppido PA, Capone R, Santoro A, Ferrante L. Tumors of the lateral ventricles. Neurosurg Rev 1991; 14 (02) 127-133
    CrossrefPubMedGoogle Scholar
  • 17 D'Angelo VAMD, Galarza M, Catapano D, Monte V, Bisceglia M, Carosi I. Lateral ventricle tumors: surgical strategies according to tumor origin and development: a series of 72 cases. Neurosurgery 2005; 56 (01) 36-45 , discussion 36–45
    CrossrefPubMedGoogle Scholar
  • 18 Gökalp HZ, Yüceer N, Arasil E. et al. Tumours of the lateral ventricle. A retrospective review of 112 cases operated upon 1970-1997. Neurosurg Rev 1998; 21 (2–3): 126-137
    CrossrefPubMedGoogle Scholar
  • 19 Majós C, Coll S, Aguilera C, Acebes JJ, Pons LC. Intraventricular mass lesions of the brain. Eur Radiol 2000; 10 (06) 951-961
    CrossrefPubMedGoogle Scholar
  • 20 Pendl G, Oztürk E, Haselsberger K. Surgery of tumours of the lateral ventricle. Acta Neurochir (Wien) 1992; 116 (2-4): 128-136
    CrossrefPubMedGoogle Scholar
  • 21 Tuffaha MSA, Guski H, Kristiansen G. (2018) Markers and immunoprofile of central nervous system tumors. In: Tuffaha MS, Guski H, Kristiansen G. eds. Immunohistochemistry in Tumor Diagnostics. Berlin: Springer International Publishing; 2018: 233-239
    CrossrefGoogle Scholar
  • 22 Waldron JS, Tihan T. Epidemiology and pathology of intraventricular tumors. Neurosurg Clin N Am 2003; 14 (04) 469-482
    CrossrefPubMedGoogle Scholar
  • 23 Ostrom QT, Gittleman H, Truitt G, Boscia A, Kruchko C, Barnholtz-Sloan JS. CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2011-2015. Neuro-oncol 2018; 20 (04, Suppl 4): iv1-iv86
    Google Scholar
  • 24 Patel DM, Schmidt RF, Liu JK. Update on the diagnosis, pathogenesis, and treatment strategies for central neurocytoma. J Clin Neurosci 2013; 20 (09) 1193-1199
    CrossrefPubMedGoogle Scholar