Importierte Systemmykose: Sind wir vorbereitet, diese Infektionen zu diagnostizieren?

Kathrin Tintelnot; Volker Rickerts

doi:10.1055/s-0041-102619

DMW – Klinischer Fortschritt, Table of Contents

Dtsch Med Wochenschr 2015; 140(12): 885-887
DOI: 10.1055/s-0041-102619

Klinischer Fortschritt

Infektiologie

Importierte Systemmykose: Sind wir vorbereitet, diese Infektionen zu diagnostizieren?

Imported systemic mycoses: are we prepared to diagnose these infections?

Kathrin Tintelnot

¹Robert Koch-Institut, FG16, Erreger von Pilz- und Parasiteninfektionen und von Mykobakteriosen, Konsiliarlabor für Kryptokokkose, Scedosporiose und importierte Systemmykosen

,

Volker Rickerts

¹Robert Koch-Institut, FG16, Erreger von Pilz- und Parasiteninfektionen und von Mykobakteriosen, Konsiliarlabor für Kryptokokkose, Scedosporiose und importierte Systemmykosen

› Author Affiliations

Abstract

Zusammenfassung

Obgleich Histoplasma capsulatum bei Tieren in Nord-Europa offenbar zu Infektionen führte, gibt es bislang keine gesicherten autochthonen humanen Fälle. Die Zunahme der Kokzidioidomykose (Valley fever) in den USA führt möglicherwiese auch dazu, dass diese Erkrankung häufiger nach Deutschland importiert wird. Es erscheint plausibel, dass der Klimawandel einen Einfluss auf die Verbreitung obligat pathogener Mykose-Erreger hat.

Abstract

Although Histoplasma capsulatum obviously has been causing infections in animals in Northern Europe, there are no proven autochthonous histoplasmoses in humans. Possibly the increase of coccidioidomycosis (valley fever) in the USA may also lead to more frequently imported infections in Germany. It seems to be plausible that climate change will influence the distribution of obligate fungal pathogens.

Schlüsselwörter

Endemische Mykosen - Histoplasmose - Kokzidioidomykose

Keywords

endemic mycoses - histoplasmosis - coccidioidomycosis

Full Text

References

Literatur
1 Antinori S. Histoplasma capsulatum: more widespread than previously thought. Am J Trop Med Hyg 2014; 90: 982-983
2 Ashbee HR, Evans EG, Viviani MA et al. Histoplasmosis in Europe: report on an epidemiological survey from the European Confederation of Medical Mycology Working Group. Med Mycol 2008; 46: 57-65
3 Barrozo LV, Mendes RP, Marques SA et al. Climate and acute / subacute paracoccidioidomycosis in a hyper-endemic area in Brazil. Int J Epidemiol 2009; 38: 1642-1649
4 Bernhardt A, von Bomhard W, Antweiler E, Tintelnot K. Molecular identification of fungal pathogens in nodular skin lesions of cats. Med Mycol 2015; 53: 132-144
5 Brown J, Benedict K, Park BJ, Thompson 3rd GR. Coccidioidomycosis: epidemiology. Clin Epidemiol 2013; 5: 185-197
6 Chakrabarti A, Bonifaz A, Gutierrez-Galhardo MC et al. Global epidemiology of sporotrichosis. Med Mycol 2015; 53: 3-14
7 Eisenberg T, Seeger H, Kasuga T et al. Detection and characterization of Histoplasma capsulatum in a German badger (Meles meles) by ITS sequencing and multilocus sequencing analysis. Med Mycol 2013; 51: 337-344
8 Fischer NM, Favrot C, Monod M et al. A case in Europe of feline histoplasmosis apparently limited to the skin. Vet Dermatol 2013; 24: 635-638
9 Garcia-Solache MA, Casadevall A. Global warming will bring new fungal diseases for mammals. mBio 2010; 1: e00061-10
10 Greer A, Ng V, Fisman D. Climate change and infectious diseases in North America: the road ahead. CMAJ 2008; 178: 715-722
11 Hagen F, Colom MF, Swinne D et al. Autochthonous and dormant cryptococcus gattii infections in Europe. Emerg Infect Dis 2012; 18: 1618-1624
12 Litvintseva AP, Marsden-Haug N, Hurst S et al. Valley fever: finding new places for an old disease: coccidioides immitis found in Washington State soil associated with recent human infection. Clin Infect Dis 2015; 60: e1-3
13 Marsden-Haug N, Goldoft M, Ralston C et al. Coccidioidomycosis acquired in Washington State. Clin Infect Dis 2013; 56: 847-850
14 Nguyen C, Barker BM, Hoover S et al. Recent advances in our understanding of the environmental, epidemiological, immunological, and clinical dimensions of coccidioidomycosis. Clin Microbiol Rev 2013; 26: 505-525
15 Park BJ, Sigel K, Vaz V et al. An epidemic of coccidioidomycosis in Arizona associated with climatic changes, 1998–2001. J Infect Dis 2005; 191: 1981-1987
16 Singh N, Huprikar S, Burdette SD et al. Donor-derived fungal infections in organ transplant recipients: guidelines of the American Society of Transplantation, infectious diseases community of practice. Am J Transplant 2012; 12: 2414-2428
17 Tintelnot K. Differential diagnoses for detection of yeasts and yeast-like organisms. Pathologe 2013; 34: 519-527