Update HIV und Neurologie

Katrin Hahn; Matthias Maschke; Christian Eggers; Ingo Wilhelm Husstedt; Gabriele Arendt

doi:10.1055/s-0041-102893

DMW - Deutsche Medizinische Wochenschrift, Table of Contents

Dtsch Med Wochenschr 2016; 141(1): 51-57
DOI: 10.1055/s-0041-102893

Fachwissen

Übersicht

Update HIV und Neurologie

Update HIV and neurology

Katrin Hahn

¹Klinik für Neurologie, Charité Berlin

,

Matthias Maschke

²Klinik für Neurologie, Krankenhaus der Barmherzigen Brüder Trier

,

Christian Eggers

³Abteilung für Neurologie, Krankenhaus der Barmherzigen Brüder Linz

,

Ingo Wilhelm Husstedt

⁴Praxis im Krankenhaus Maria Frieden, Telgte / Medizinische Fakultät der Westfälischen Wilhelms Universität Münster

,

Gabriele Arendt

⁵Klinik für Neurologie, Universitätsklinikum Düsseldorf

› Author Affiliations

Abstract

Zusammenfassung

Die Fortschritte der antiretroviralen Therapie haben die HIV-Infektion zu einer chronischen Krankheit gemacht. Der Übersichtsartikel fasst zusammen, was ein Leben mit HIV aus neurologischer Sicht über Jahrzehnte hinweg für die Betroffenen bedeutet. Neben klinischen und pathophysiologischen Aspekten des HIV-assoziierten kognitiven Defizits (HAND) werden auch periphere HIV-Manifestationen beleuchtet. Der Artikel berücksichtigt Komorbiditäten wie die in der Inzidenz ansteigende Neurolues, sowie die Hepatitis C, da beide durch ihr Interaktionsspektrum mit dem HI-Virus insbesondere für den Neurologen von großem Interesse sind.

Abstract

With modern antiretroviral drug regimens, HIV-infected people are living longer and HIV has transformed into a chronic illness. The review summarizes pathophysiological as well as clinical aspects of a chronic infection from a neurological point of view including neurocognitive impairment, depression, neuropathies and myopathies. It also draws attention to comorbidities such as syphilis and hepatitis C. They are of particular neurological interest because of the interaction of the pathogens.

Schlüsselwörter

NeuroAIDS - HAND - Depression - Neurolues - Hepatitis C

Keywords

NEUROAIDS - HAND - depression - neurolues - hepatitis C

Full Text

References

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