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DOI: 10.1055/s-0041-109739
Schwarzkümmel (Nigella sativa L.)
Ein traditionell genutztes Gesundheitsmittel mit potenziell neuen IndikationenPublication History
Publication Date:
09 February 2016 (online)
Zusammenfassung
Nigella sativa wird traditionell als Gesundheits- bzw. Nahrungsergänzungsmittel verwendet. Untersuchungen in den letzten Jahren, in denen gezielt Stoffwechselreaktionen nach oraler Verabreichung der Samen bzw. des daraus kalt gepressten Öls gemessen wurden, zeigen, dass der Stoffwechsel günstig beeinflusst wird. In klinischen Studien wurde nachgewiesen, dass zumindest eine add-on-Therapie bei Diabetes oder bei Fettstoffwechselstörungen positive Zusatzeffekte generiert. Offen ist im Moment noch die zu verabreichende Dosis an Samen bzw. des Öls, da je nach Herkunft unterschiedliche Ausbeuten erhalten werden und zusätzlich der Gehalt an Thymochinon, dem aktiven Inhaltsstoff, erheblichen Schwankungen unterliegt.
Summary
Black cumin (Nigella sativa L.). A traditional plant remedy with potentially new indications
Nigella sativa is traditionally used as a health and dietary supplement. In recent years studies have been undertaken to measure metabolic reactions with reference to the oral administration of seeds as well as the cold pressed oil. The studies have exhibited a positive effect of these black cumin products on metabolism. Similarly clinical trials have demonstrated that (at least) an add-on therapy generates positive additional effects on the treatment of diabetes or lipometabolic disorder. However, the dose of seeds or oil to be orally administered is still undecided due to the variation in black cumin yields and the thymoquinone content.
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