Subscribe to RSS
DOI: 10.1055/s-0041-1724577
Anxiety and Cancerophobia in Patients With Small Gastrointestinal Subepithelial Lesions and Tumours: Baseline Results of a Prospective Study (QUALI-BANDING-SET)
Aims Small subepithelial lesions (SEL) or subepithelial tumours (SET) confirmed once characterized by endoscopic ultrasound (EUS), could generate anxiety and fear of cancer. Main aim: to assess the anxiety burden and cancerophobia in patients with small-sized SELs diagnosis or SETs under EUS surveillance. Secondary aims: to evaluate possible factors or patients’ characteristics influencing on anxiety or fear of cancer degree.
Methods Observational prospective study. Consecutive inclusion of all patients with a small-sized SEL diagnosis (requiring an EUS performance), or patients with a previously catalogued SET under echoendoscopy surveillance. Evaluation of the anxiety-distress degree and fear of cancer using two specific designed and validated instruments-questionnaires: Hospital Anxiety and Depression Scale (HADS), anxiety and depression subscales [0-7 points=normal; 8-10=borderline; 11-21=pathologic], and global-distress scale [0-10 points=normal; 11-17=borderline; 18-42=pathologic]; and Cancer Worry Scale (CWS) [6-10 points=low; 11-15=moderate; 16-20=high; 21-24=very high]. ClinicalTrials.gov register: NCT04316000.
Results Two participating centres, 40 patients (inclusion period: September 2019 - February 2020). Mean HADS-anxiety: 7.2 (+/- 4.3) [= borderline anxiety]; HADS-distress: 11.4 (+/- 7.7) [= borderline distress]; CWS: 11.0 (+/- 4.1) [= moderate concern]. HADS-anxiety and CWS correlation coefficient: 0.75. Belief on probability of having GI cancer now: 20.7 % (+/- 23.6); belief on probability of getting GI cancer in 10 years: 28.6 % (+/- 24.3). Impact on quality of life: Yes 40 % (16/40). Female sex (n-26) vs. male (n-14) subanalysis: HADS-anxiety 8.0 vs. 5.9; HADS-distress 12.7 vs. 9.0; CWS 11.5 vs. 9.9. Family history of cancer YES (n-29) vs. NO (n-11) subanalysis: HADS-anxiety 8.1 vs. 5.0; HADS-distress 12.7 vs. 8.0; CWS 11.7 vs. 9.1.
HADS anxiety |
HADS distress |
Cancer Worry Scale (CWS) |
YES Impact on quality of life |
|
---|---|---|---|---|
Female sex (n-26) |
8.0 |
12.7 |
11.5 |
53.9 % (n-14) |
Male sex (n-14) |
5.9 |
9.0 |
9.9 |
14.3 % (n-2) |
YES family history of cancer (n-29) |
8.1 |
12.7 |
11.7 |
48.3 % (n-14) |
NO family history of cancer (n-11) |
5.0 |
8.0 |
9.1 |
18.2 % (n-2) |
Conclusions Patients with SEL diagnosis or SET under EUS surveillance present a moderate anxiety-distress degree and a moderate concern about having cancer, partially affecting their quality of life. Family history of cancer and female gender are factors that can increase anxiety and cancerophobia degree.
Citation: Bas-Cutrina F, Loras C, García-Ibáñez ME et al. eP78 ANXIETY AND CANCEROPHOBIA IN PATIENTS WITH SMALL GASTROINTESTINAL SUBEPITHELIAL LESIONS AND TUMOURS: BASELINE RESULTS OF A PROSPECTIVE STUDY (QUALI-BANDING-SET). Endoscopy 2021; 53: S122.
#
Publication History
Article published online:
19 March 2021
© 2021. European Society of Gastrointestinal Endoscopy. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany