Endoscopy 2021; 53(S 01): S122
DOI: 10.1055/s-0041-1724578
Abstracts | ESGE Days
ESGE Days 2021 Digital poster exhibition

Endoscopic Resection of Type I Gastric Neuroendocrine Neoplasia: A Systematic Review

G Esposito
1   Sapienza University of Rome, Sant’Andrea Hospital, Department of Medical-Surgical Sciences and Translational Medicine, Rome, Italy
,
F Panzuto
2   Sapienza University of Rome, Digestive Disease Unit, Sant’Andrea Hospital, ENETS Center of Excellence, Rome, Italy
,
L Magi
3   Sapienza University of Rome, Department of Translational and Precision Medicine, Rome, Italy
,
M Rinzivillo
2   Sapienza University of Rome, Digestive Disease Unit, Sant’Andrea Hospital, ENETS Center of Excellence, Rome, Italy
,
B Annibale
1   Sapienza University of Rome, Sant’Andrea Hospital, Department of Medical-Surgical Sciences and Translational Medicine, Rome, Italy
2   Sapienza University of Rome, Digestive Disease Unit, Sant’Andrea Hospital, ENETS Center of Excellence, Rome, Italy
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    Aims Although relatively uncommon, the incidence of type I gastric neuroendocrine neoplasia (NEN) has been rising over time. Since they are considered indolent neoplasms, with low metastatic potential, endoscopic resection is the treatment of choice. However, correct endoscopic management is not well established. This systematic review aimed to investigate which is the best endoscopic technique to achieve complete resection in type I gastric NEN.

    Methods Medline through Pubmed and Scopus databases was conducted on August 2020 and a systematic review of the current literature was conducted in accordance with the PRISMA statement.

    Results Above the 675 studies retrieved, 6 were finally considered eligible. Main endoscopic resection techniques described were mucosal resection (EMR) and submucosal dissection (ESD), one reported resection by snare or forceps. Both techniques showed similar results for complete resection (97.4 % vs 98.7 %) and en bloc resection (92.3 % vs 96.3 %) with ESD and EMR, respectively. Even if ESD was associated with a higher rate of complications than EMR (11.7 % vs 5.4 %) this difference was not statistically significant (p = 0.17). Either bleeding or perforation occurred with both techniques. Only one study reported a 100 % rate of complete resection with snare and/or forceps without complications, but the recurrence rate was 66,3 %. Conversely, EMR and ESD showed a lower rate of recurrence, 18.2 % and 11.5 % respectively, with a significant difference compared to snare and/or forceps resection (p < 0,001).

    Conclusions To date, there are no sufficient data to provide superiority of a given endoscopic technique compared with others. Either ESD or EMR seems to be effective with a relatively low rate of recurrence.

    Citation: Esposito G, Panzuto F, Magi L et al. eP79 ENDOSCOPIC RESECTION OF TYPE I GASTRIC NEUROENDOCRINE NEOPLASIA: A SYSTEMATIC REVIEW. Endoscopy 2021; 53: S122.


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    Publikationsverlauf

    Artikel online veröffentlicht:
    19. März 2021

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