Subscribe to RSS
![](/products/assets/desktop/img/oa-logo.png)
DOI: 10.1055/s-0041-1727762
Multi-resistant pathogens in patients of a university ear, nose and throat clinic
Multi-resistant pathogens (MRE) represent a worldwide challenge, require special hygienic measures and make therapy for affected patients more difficult. The significance of MRE in ENT patients is still unclear. A retrospective evaluation of positive MRE smears (MRSA, VRE, MRGN) in the period from 2008 to 2017 was performed with regard to frequency, localization and pathogen-associated infections.
We identified n=482 cases tested positive for MRE. MRSA (n=157) accounted for 32.6 % , VRE (n=49) for 10.2 % , ESBL (n=111) for 23.0 % , MRGN+FQ (n=155) for 32.2 % and MRGN+CR (n=10) for 2.1 % . Overall, both performed and MRE-positive smears increased significantly (2008: 95 of 316 positive; 2017: 242 of 2067 positive, p<0.001). Colonizations with MRSA (ear/nose, n=126; 80.3 % ) and MRGN+CR (trachea/tracheostoma, n=4; 40.0 % ) were most evident. VRE, ESBL and MRGN+FQ were most frequently detected in the anal/rectal region (n=41, 83.7 % ; n=97; 87.4 % and n=108; 69.7 % , respectively). Patients with MRSA were significantly more likely to have pathogen-associated infections (n=89; 56.7 % , p<0.001) than patients with other MRE. VRE (n=45; 91.8 % ) caused the most common asymptomatic colonization.
MRE occur ubiquitously in the ENT area. Here the most frequent MRE colonization is caused by MRSA and MRGN+CR. MRSA also cause the most common symptomatic infections, while VRE cause asymptomatic colonization in most cases. This should be taken into account when choosing antibiotic therapy. In addition, against the background of increasing MRE numbers, common hygiene concepts should be strictly adhered to and MRE development/spread should be reduced by antibiotic stewardship concepts.
Poster-PDF A-1570.pdf
#
Conflict of interest
Der Erstautor gibt keinen Interessenskonflikt an.
Address for correspondence
Publication History
Article published online:
13 May 2021
© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany