Managing Postembolization Syndrome–Related Pain after Uterine Fibroid Embolization

Patricia Chan; Kirema Garcia-Reyes; Julie Cronan; Janice Newsome; Zachary Bercu; Bill S. Majdalany; Neil Resnick; Judy Gichoya; Nima Kokabi

doi:10.1055/s-0041-1731406

Seminars in Interventional Radiology, Table of Contents

Semin intervent Radiol 2021; 38(03): 382-387
DOI: 10.1055/s-0041-1731406

Clinical Corner

Managing Postembolization Syndrome–Related Pain after Uterine Fibroid Embolization

Patricia Chan

¹Division of Interventional Radiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia

,

Kirema Garcia-Reyes

¹Division of Interventional Radiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia

,

Julie Cronan

¹Division of Interventional Radiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia

,

Janice Newsome

¹Division of Interventional Radiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia

,

Zachary Bercu

¹Division of Interventional Radiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia

,

Bill S. Majdalany

¹Division of Interventional Radiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia

,

Neil Resnick

¹Division of Interventional Radiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia

,

Judy Gichoya

¹Division of Interventional Radiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia

,

Nima Kokabi

¹Division of Interventional Radiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia

› Author Affiliations

Abstract

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References

References
1 Stewart EA, Cookson CL, Gandolfo RA, Schulze-Rath R. Epidemiology of uterine fibroids: a systematic review. BJOG 2017; 124 (10) 1501-1512
2 Zimmermann A, Bernuit D, Gerlinger C, Schaefers M, Geppert K. Prevalence, symptoms and management of uterine fibroids: an international internet-based survey of 21,746 women. BMC Womens Health 2012; 12 (01) 6
3 Lampmann LE, Lohle PN, Smeets A. et al. Pain management during uterine artery embolization for symptomatic uterine fibroids. Cardiovasc Intervent Radiol 2007; 30 (04) 809-811
4 Ravina JH, Herbreteau D, Ciraru-Vigneron N. et al. Arterial embolisation to treat uterine myomata. Lancet 1995; 346 (8976): 671-672
5 American College of Obstetricians and Gynecologists. ACOG practice bulletin. Alternatives to hysterectomy in the management of leiomyomas. Obstet Gynecol 2008; 112 (2, Pt 1): 387-400
6 Keung JJ, Spies JB, Caridi TM. Uterine artery embolization: a review of current concepts. Best Pract Res Clin Obstet Gynaecol 2018; 46: 66-73
7 Hovsepian DM, Mandava A, Pilgram TK. et al. Comparison of adjunctive use of rofecoxib versus ibuprofen in the management of postoperative pain after uterine artery embolization. J Vasc Interv Radiol 2006; 17 (04) 665-670
8 Roth AR, Spies JB, Walsh SM, Wood BJ, Gomez-Jorge J, Levy EB. Pain after uterine artery embolization for leiomyomata: can its severity be predicted and does severity predict outcome?. J Vasc Interv Radiol 2000; 11 (08) 1047-1052
9 Hovsepian DM, Siskin GP, Bonn J. et al; CIRSE Committee, SIR Standards of Practice Committee. Quality improvement guidelines for uterine artery embolization for symptomatic leiomyomata. J Vasc Interv Radiol 2004; 15 (06) 535-541
10 Ganguli S, Faintuch S, Salazar GM, Rabkin DJ. Postembolization syndrome: changes in white blood cell counts immediately after uterine artery embolization. J Vasc Interv Radiol 2008; 19 (03) 443-445
11 Spencer EB, Stratil P, Mizones H. Clinical and periprocedural pain management for uterine artery embolization. Semin Intervent Radiol 2013; 30 (04) 354-363
12 Pasero C, Stannard D. The role of intravenous acetaminophen in acute pain management: a case-illustrated review. Pain Manag Nurs 2012; 13 (02) 107-124
13 Chaabane S, Hoffman C, Kim G. et al. A prospective, double-blind, randomized controlled study evaluating the effects of two new IV medications, IV acetaminophen and/or IV ibuprofen, on standard of care pain and antiemetic management in uterine fibroid embolization patients. J Vasc Interv Radiol 2017; 28 (02) S47-S48
14 Bilhim T, Pisco JM. The role of nonsteroidal anti-inflammatory drugs (NSAIDs) in the management of the post-embolization symptoms after uterine artery embolization. Pharmaceuticals (Basel) 2010; 3 (06) 1729-1738
15 Siskin GP, Stainken BF, Dowling K, Meo P, Ahn J, Dolen EG. Outpatient uterine artery embolization for symptomatic uterine fibroids: experience in 49 patients. J Vasc Interv Radiol 2000; 11 (03) 305-311
16 Hansen RN, Pham AT, Boing EA, Lovelace B, Wan GJ, Urman RD. Reduced length of stay and hospitalization costs among inpatient hysterectomy patients with postoperative pain management including IV versus oral acetaminophen. PLoS One 2018; 13 (09) e0203746-e0203746
17 Mahajan L, Mittal V, Gupta R, Chhabra H, Vidhan J, Kaur A. Study to compare the effect of oral, rectal, and intravenous infusion of paracetamol for postoperative analgesia in women undergoing cesarean section under spinal anesthesia. Anesth Essays Res 2017; 11 (03) 594-598
18 Johnson RJ, Nguyen DK, Acosta JM, O'Brien AL, Doyle PD, Medina-Rivera G. Intravenous versus oral acetaminophen in ambulatory surgical center laparoscopic cholecystectomies: a retrospective analysis. P&T 2019; 44 (06) 359-363
19 Raffa RB. Pharmacology of oral combination analgesics: rational therapy for pain. J Clin Pharm Ther 2001; 26 (04) 257-264
20 Bresalier RS, Sandler RS, Quan H. et al; Adenomatous Polyp Prevention on Vioxx (APPROVe) Trial Investigators. Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med 2005; 352 (11) 1092-1102
21 Nissen SE, Yeomans ND, Solomon DH. et al; PRECISION Trial Investigators. Cardiovascular safety of celecoxib, naproxen, or ibuprofen for arthritis. N Engl J Med 2016; 375 (26) 2519-2529
22 Pisco JM, Bilhim T, Duarte M, Santos D. Management of uterine artery embolization for fibroids as an outpatient procedure. J Vasc Interv Radiol 2009; 20 (06) 730-735
23 Freire GMG, Cavalcante RN, Motta-Leal-Filho JM. et al. Controlled-release oxycodone improves pain management after uterine artery embolisation for symptomatic fibroids. Clin Radiol 2017; 72 (05) 428.e1-428.e5
24 Saibudeen A, Makris GC, Elzein A. et al. Pain management protocols during uterine fibroid embolisation: a systematic review of the evidence. Cardiovasc Intervent Radiol 2019; 42 (12) 1663-1677
25 Waldron NH, Jones CA, Gan TJ, Allen TK, Habib AS. Impact of perioperative dexamethasone on postoperative analgesia and side-effects: systematic review and meta-analysis. Br J Anaesth 2013; 110 (02) 191-200
26 Wang M, Kohi MP. The rationale, design, and methods of a randomized, controlled trial to evaluate the efficacy of single-dose dexamethasone in reducing post-embolization syndrome in patients undergoing uterine artery embolization. Contemp Clin Trials Commun 2018; 12: 85-89
27 Kim SY, Chang CH, Lee JS, Kim YJ, Kim MD, Han DW. Comparison of the efficacy of dexmedetomidine plus fentanyl patient-controlled analgesia with fentanyl patient-controlled analgesia for pain control in uterine artery embolization for symptomatic fibroid tumors or adenomyosis: a prospective, randomized study. J Vasc Interv Radiol 2013; 24 (06) 779-786
28 Raldi FV, Nascimento RD, Sato FRL, Santos LM, Amorim JBO, de Moraes MB. Evaluation of the impact of preoperative use of dexamethasone and cyclobenzaprine in surgical extraction of lower third molars on trismus by electromyographic analysis. Oral Maxillofac Surg 2019; 23 (04) 395-405
29 Hwang SK. Advances in the treatment of chronic pelvic pain: a multidisciplinary approach to treatment. Mo Med 2017; 114 (01) 47-51
30 Rasuli P, Jolly EE, Hammond I. et al. Superior hypogastric nerve block for pain control in outpatient uterine artery embolization. J Vasc Interv Radiol 2004; 15 (12) 1423-1429
31 Park PJ, Kokabi N, Nadendla P, Lindsey T, Dariushnia SR. Efficacy of intraprocedural superior hypogastric nerve block in reduction of postuterine artery embolization narcotic analgesia use. Can Assoc Radiol J 2020; 71 (01) 75-80
32 Pereira K, Morel-Ovalle LM, Wiemken TL. et al. Intraprocedural superior hypogastric nerve block allows same-day discharge following uterine artery embolization. J Vasc Interv Radiol 2020; 31 (03) 388-392
33 Stewart JK, Patetta MA, Burke CT. Superior hypogastric nerve block for pain control after uterine artery embolization: effect of addition of steroids on analgesia. J Vasc Interv Radiol 2020; 31 (06) 1005-1009.e1
34 Hoffman C, Yarosh C, Boyd E. et al. Superior hypogastric nerve block in uterine fibroid embolization patients with radial artery access: vascular considerations, anesthetic choices, and rescue options. J Vasc Interv Radiol 2018; 29 (05) 745-747
35 Noel-Lamy M, Tan KT, Simons ME, Sniderman KW, Mironov O, Rajan DK. Intraarterial lidocaine for pain control in uterine artery embolization: a prospective, randomized study. J Vasc Interv Radiol 2017; 28 (01) 16-22
36 Duvnjak S, Andersen PE. Intra-arterial lidocaine administration during uterine fibroid embolization to reduce the immediate postoperative pain: a prospective randomized study. CVIR Endovasc 2020; 3 (01) 10
37 Katsumori T, Miura H, Yoshikawa T, Seri S, Kotera Y, Asato A. Intra-arterial lidocaine administration for anesthesia after uterine artery embolization with trisacryl gelatin microspheres for leiomyoma. J Vasc Interv Radiol 2020; 31 (01) 114-120
38 Caridi T. Intra-arterial lidocaine is not found to be effective for reducing pain after uterine fibroid embolization in a retrospective study: now what?. J Vasc Interv Radiol 2020; 31 (01) 121-122
39 Keyoung JA, Levy EB, Roth AR, Gomez-Jorge J, Chang TC, Spies JB. Intraarterial lidocaine for pain control after uterine artery embolization for leiomyomata. J Vasc Interv Radiol 2001; 12 (09) 1065-1069
40 Resnick NJ, Kim E, Patel RS, Lookstein RA, Nowakowski FS, Fischman AM. Uterine artery embolization using a transradial approach: initial experience and technique. J Vasc Interv Radiol 2014; 25 (03) 443-447
41 Nakhaei M, Mojtahedi A, Faintuch S, Sarwar A, Brook OR. Transradial and transfemoral uterine fibroid embolization comparative study: technical and clinical outcomes. J Vasc Interv Radiol 2020; 31 (01) 123-129
42 Liu LB, Cedillo MA, Bishay V. et al. Patient experience and preference in transradial versus transfemoral access during transarterial radioembolization: a randomized single-center trial. J Vasc Interv Radiol 2019; 30 (03) 414-420
43 Fischman AM, Swinburne NC, Patel RS. A technical guide describing the use of transradial access technique for endovascular interventions. Tech Vasc Interv Radiol 2015; 18 (02) 58-65