Surgical Ablation of Permanent Atrial Fibrillation: Age, LV Dilatation, Obesity

Susanne Rohrbach; Elisabeth Dominik; Nikolas Mirow; Sebastian Vogt; Andreas Böning; Bernd Niemann

doi:10.1055/s-0041-1731772

The Thoracic and Cardiovascular Surgeon, Inhaltsverzeichnis

Thorac Cardiovasc Surg 2023; 71(04): 264-272
DOI: 10.1055/s-0041-1731772

Original Cardiovascular

Surgical Ablation of Permanent Atrial Fibrillation: Age, LV Dilatation, Obesity

Susanne Rohrbach‡^*

¹Institute of Physiology, Justus Liebig University Giessen, Hessen, Germany

,

Elisabeth Dominik‡^*

²Department of Cardiac and Vascular Surgery, University Hospital of Giessen and Marburg, Giessen and Justus-Liebig-University Giessen, Giessen, Germany

,

Nikolas Mirow

³Department of Cardiac and Vascular Surgery, University Hospital of Giessen and Marburg, Marburg Philipps University Marburg, Marburg, Germany

,

Sebastian Vogt

³Department of Cardiac and Vascular Surgery, University Hospital of Giessen and Marburg, Marburg Philipps University Marburg, Marburg, Germany

,

Andreas Böning

²Department of Cardiac and Vascular Surgery, University Hospital of Giessen and Marburg, Giessen and Justus-Liebig-University Giessen, Giessen, Germany

,

Bernd Niemann

²Department of Cardiac and Vascular Surgery, University Hospital of Giessen and Marburg, Giessen and Justus-Liebig-University Giessen, Giessen, Germany

› Institutsangaben

Abstract

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Abstract

Objectives Although concomitant surgical ablation can help to reach freedom from atrial fibrillation (FREEAF) even in patients with permanent atrial fibrillation (AF), some cardiac surgeons hesitate to perform concomitant ablation to avoid perioperative risk escalation. Here, we investigated outcome and predicators of therapeutic success of concomitant surgical ablation in an all-comers study.

Methods Ablation-naïve patients with formerly accepted permanent AF (FAP, n = 41) or paroxysmal AF (parAF, n = 24) underwent concomitant epicardial bipolar radio frequency ablation and implantable loop recorder (ILR) at two surgical departments. Follow-up examination for 24 months included electrocardiogram, ILR readout, 24h Holter monitoring, echocardiography, and blood sampling.

Results Eighty-six percent of parAF and 70% of FAP patients reached FREEAF (month 24). Mortality was low (parAF/FAP: 5.3 ± 0.2%/4.1 ± 0.3%; p < 0.05; EuroScoreII; 6.1 ± 0.7%/6.4 ± 0.4%, p = ns) and no strokes occurred. FREEAF induced atrial reverse remodeling (left atrial [LA] diameter: −6.7 ± 2.2 mm) and improved cardiac function (left ventricular ejection fraction [LVEF]: +7.3 ± 2.8%), while AF resulted in further atrial dilation (+8.0 ± 1.0 mm, p < 0.05) and LVEF reduction (−7.0 ± 1.3%, p < 0.05). Higher LV (odds ratio [OR]: 1.164) and LA diameter (OR: 1.218), age (OR: 1.180) and body mass index (BMI) (OR: 1.503) increased the risk factors of AF recurrence. Patients remaining in sinus rhythm (SR) demonstrated a decrease in BMI, while AF recurrence was associated with stable overweight. Further aging did not reduce FREEAF.

Conclusions Long-term SR is achievable by concomitant surgical ablation even in FAP patients. Therefore, it should be offered routinely. Obesity influences therapeutic long-term success but may also offer addressable therapeutic targets to reach higher FREEAF rates.

Keywords

surgical atrial fibrillation therapy - obesity - outcomes

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Referenzen

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