Keywords
gossypiboma - foreign body - surgery - complications
Introduction
“Gossypiboma” is a term used to refer to a nonabsorbable material, such as gauze sponges
or swabs, accidentally left inside a patient's body cavity during an operation.[1] It is a combination of two words: the Latin word “Gossypium,” meaning cotton, and
the Swahili word “boma,” meaning a place of concealment.[1] In the literature, gossypiboma, a retained surgical gauze or sponge, may also be
referred to as “textiloma.” Although gossypiboma is preventable and should never happen,
its incidence is estimated to be as high as between one in 1,000 and one in 10,000
surgeries.[2]
Gossypiboma is a major safety violation. It is reported that it accounts for 50% of
malpractice claims[2] and is generally associated with medicolegal consequences. Because of its nonspecific
manifestation, the diagnosis of gossypiboma may easily be overlooked.[3] However, it may cause serious morbidities or may become symptomatic. It may mimic
a hematoma, an abscess, a cyst, a loculated empyema, infectious diseases, or even
malignant tumors in radiological examination. In this article, we report four retained
surgical sponge cases. The first case presented mild symptoms and caused suspicion
of malignancy. In the second case, a probable abscess was thought of as a differential
diagnosis, while the third and fourth cases suffered from wound discharges for 15
years and 6 months, respectively.
Case 1
A 64-year-old female was referred to the outpatient clinic with the chief complaint
of hemoptysis once a week with vague chest pain for 2 years. According to the medical
history received from the patient, she had had an urgent thoracotomy due to a hematoma
following a thyroidectomy operation 9 years before. She was a former smoker, with
a 20 pack-year history, but had ceased 9 years prior. After a chest computed tomography
(CT), a 50*31 mm mass located in the right upper lobe was noticed ([Fig. 1]). There were no signs of calcification, mediastinal lymphadenopathy, or pleural
effusion. In positron emission tomography (PET), the standard uptake value was measured
at 9.5 with no other distant uptake. Her forced expiratory volume in the first second
was 2.57 (%103,5). Flexible bronchoscopy was unremarkable. Wedge resection of the
mass in the upper lobe was performed in a redo thoracotomy. On the back table, a 3
cm incision was made, and a gauze was seen inside the specimen. The histopathological
examination reported a foreign body granulation tissue and fibrous capsule formation.
Cellulosic fibers were detected inside the cells. Therefore, the case was diagnosed
as a gossypiboma/textiloma. Postoperative course was uneventful, and the patient was
discharged on the fourth postoperative day.
Fig. 1 Fluorodeoxyglucose-avid right upper lobe solid mass.
Case 2
A 75-year-old male was referred to our outpatient clinic with dyspnea on exertion
for 2 months. In chest CT, an 83 × 78 × 73 mm, heterogenous, encapsulated, and partially
calcified mass was observed in left lower lobe ([Fig. 2]). His medical history included a coronary bypass graft 20 years ago. His pulmonary
function tests were within normal range. Surgery was recommended with a preliminary
diagnosis of a limited abscess with calcific margins formed after the bypass procedure.
In surgery, there were dense adhesions to vertebral bodies, diaphragm, and the aorta.
An extrapulmonary and extrapericardial mass was removed. Pathological examination
reported hyaline fibrosis with foreign body reaction. The wall thickness was measured
at 1.5 cm with some calcified areas. After an uneventful postoperative course, the
patient was discharged on the fifth day.
Fig. 2 A giant, heterogenous, encapsulated, focally calcified, cystic mass was seen in the
left lower lobe area.
Case 3
A 65-year-old male consulted our clinic for purulent wound discharges from two cutaneous
fistulas on the xyphoid and right lateral chest wall. The patient had suffered from
continuous wound discharges for 15 years, after a mitral valve replacement surgery
that had taken place at that time. Gossypiboma was the preliminary diagnosis, and
a chest CT was implemented to confirm ([Fig. 3]). A retained gauze sponge without radiopaque lines was removed near the pericardium.
Wound debridement tissues were sent for pathological examination, which reported them
to be abscess formation and fibrosis. Methicillin-sensitive Staphylococcus aureus was isolated, and the patient received antibiotics and negative-pressure wound therapy
to induce granulation. The postoperative period was otherwise uneventful, and he was
discharged on the eighth day.
Fig. 3 A paracardiac gossypiboma in its characteristic spongiform appearance.
Case 4
A 19-year-old male reached out to our outpatient clinic with wound discharge. Following
a stab wound 6 months prior, he had had an emergency thoracotomy and a laparotomy
simultaneously. The complaint was a purulent discharge from the chest drain's incision
scar. The otherwise healthy patient had a diagnostic CT ([Fig. 4]), which showed no visible radiopaque marking in the foreign body, but considering
the patient's operation history and wound discharge, the preliminary diagnosis included
gossypiboma and empyema. Surgery for sponge excision and decortication for empyema
was performed and pathological examination confirmed the diagnosis. He was discharged
on the fifth day after an uneventful postoperative course.
Fig. 4 An intrathoracic heterogeneous solid mass with undulant borders.
Discussion
The diagnosis of gossypiboma may be overlooked because of its rare occurrence and
low frequency of suspicion. It is important to remember that gossypiboma can be a
complication of any surgical procedure. In a review article with a total of 254 cases,
the risk factors were reported as emergency procedures, lengthy procedures, unexpected
changes in the procedures, cases involving more than one body cavity or surgical field,
patients with a high body mass index, staffs' shift changes, staffs' inadequate communication,
incomplete count of surgical gauze sponges, absence of a brief standardized sponge
counting policy, and usage of nonradiopaque sponges.[4] The cases presented earlier are exemplary of these circumstances. In the first case,
the patient had had an urgent thoracotomy for a hematoma. The second and third cases
presented lengthy operations during which the medical staff's attention levels may
diminish. Case 4 presented a case of emergent trauma resulting from a stab wound and
involving multicavities in the procedure. All patients in this group of cases seem
to comply with the risk factors described above.
Another important aspect of gossypibomas is that their symptoms' onset may take place
early or significantly late, that is, after several years. In our report, there were
long periods between the operation where the gossypiboma was left and its eventual
removal. In our first case, there were 9 years in between these two points, including
2 years of mild hemoptysis. In our second case, the patient spent two clinically silent
decades with an intrathoracic gossypiboma. The third case presented continuous wound
discharge for 15 years without the patient seeking any further advice. In the fourth
case, a young male complained of wound discharge for 6 months before a gossypiboma
was suspected. Most of the literature on intrathoracic gossypibomas consists of case
reports, where we encountered widely varying for the period between the initial procedure
and retrieval. In one of the largest series, it ranged from 1 to 120 months, with
a mean of 30.6 months.[5] One review article reported that the average time of gossypiboma discovery was 6.9
years, with 38% of the cases being discovered within the first year.[4] However, in one case report, authors reported that gauze sponge was hidden for 52
years without any symptoms.[6] The numerous examples found in the literature, and particularly the inconsistency
these show in relation to the symptoms presented and their onset, provide evidence
that there is no single clinical pattern for gossypibomas. For this reason, regardless
of the number of years passed, a patient's history of surgical procedure should, on
its own, be enough for a doctor to include gossypibomas in the list of differential
diagnoses.
In addition to the symptoms' onset likelihood of being postponed for several years,
clinical presentation and patients' reason for admission may be unclear. Clinical
presentation of intrathoracic gossypiboma is vague, as patients with this condition
may present with fever, cough, hemoptysis, weight loss, dyspnea, shoulder pain, wound
discharge, or, even, they may be entirely asymptomatic. A further complication lies
in the fact that these signs are frequently attributed to a range of lung diseases.
In these series, the first patient's main complaint was hemoptysis, which could be
seen as the clinical presentation of a lung tumor. Added the opacity's fluorodeoxyglucose
(FDG) avidity, it would be natural to include primary lung malignancies in differential
diagnoses. It is also reported that gossypibomas may show low, moderate, or high affinity
to FDG in PET.[7]
[8] Our first case showed moderate amount of FDG affinity, contributing to the uncertainty
of the diagnosis and suggesting neoplasm.
On the other hand, this patient's refusal to a new operation for 2 years highlighted
the fact that, over this period, the radiological opacity ([Fig. 1]) did not present any progress in size, pointing to the probability of a benign disease.
This, along with the history of her previous urgent thoracotomy, led us to the presumptive
diagnosis of gossypiboma, later confirmed by the back table examination. The second
case's radiological image displayed the characteristics of a cyst with a smooth circular
shape as well as dense structures inside the lesion, which could suggest the presence
of an abscess when considering the lesion's calcific borders. Due to the proximity
to the pulmonary arteries, the possibility of an aneurysm should be considered, but
the lesion's lack of any contrast medium inside makes this diagnosis highly unlikely.
Low incidence, low rate of suspicion, and nonspecific findings on chest CT could be
the main causes of unnoticed or undiagnosed thoracic gossypibomas.[9] In late recognition, it may mimic hematoma,[10] abscess, aspergilloma,[11]
[12] echinococcal cyst,[13]
[14] loculated empyema, bronchiectasis,[15] granulomatous diseases, or even malignancies.[9]
Even though chest CT does not provide a precise and reliable diagnosis of intrathoracic
gossypiboma, it remains the most effective tool when trying to identify it. It would
be likely to find the spongiform appearance characteristic of gossypiboma/textiloma
([Fig. 3]). However, thoracic textilomas may lose their spongiform appearance, as air bubbles
could disappear due to the pleura's absorption capacity.[16] This also means that the radiological image may simply show a nonspecific solid
mass. As a matter of fact, three of the cases presented here lost the air entrapment
inside the foreign gauze ([Figs. 1], [2], and [4]). This could be the reason why, in literature, the main consensus regarding radiological
findings is their heterogeneity. Even with modern investigational tools, it remains
difficult to accurately diagnose all gossypibomas. Nevertheless, they should be included
in the differential diagnosis of all atypical chest lesions in any patient who has
had an operative procedure previously. In the reviewed reports, however, physicians
included gossypiboma as a differential diagnosis in only 39% of the cases.[4]
Gossypiboma is undoubtedly a major safety violation and can cause considerable medicolegal
problems. At the same time, it is a preventable complication. Rules exist requiring
the exclusive usage of sponges with radiopaque markers. Although it is known that
the radiopaque marked sponges were widely used in our country for many years, in all
four of the patients, who had their previous surgeries in other hospitals, the retained
gauze sponges had no radiopaque marker, further diminishing the probability of finding
accurate preoperative diagnosis as a consequence. Over and above, there should be
strict, clear, and standardized policies to count the sponges. If the counting does
not match, Raytec sponges can easily be recognized with C-armed scopes, and immediately
be removed. Thus, the patients would not suffer from further complications, additional
costs, and possible morbidities of redo surgeries. What is more, the surgery team
would avoid the burden of medicolegal consequences.
Conclusion
Patients suffering from retained surgical sponges may have serious complications in
the early postoperative period, or these may remain silent in the body cavity for
many years without any symptoms. Undoubtedly, there is major safety violation in both
situations. It must be noted that they may cause serious medicolegal consequences.
These case series emphasize that intrathoracic gossypiboma can cause nonspecific symptoms
and may emerge even after 20 years. Despite its rarity, clinicians must include gossypiboma
in differential diagnoses for patients who had a previous surgery. Lastly, we recommend
using the radiopaque gauzes routinely, along with the careful counting of the gauzes
before finishing each operation. Albeit surgery itself is diagnostic and curative,
prevention is always easier and better.
