Susan S. Kais et al. Continuous negative external pressure (cNEP) reduces respiratory impairment during screening colonoscopy: a pilot study
Sedative drugs used for gastrointestinal endoscopy may increase the collapsibility of the upper airway leading to respiratory impairment and apnea. This small, open-label, comparative pilot study examines the utility of a device that provides continuous negative external pressure (cNEP) to the upper airway for the prevention of respiratory impairment. The device, a cNEP collar, significantly reduced the number of episodes of respiratory impairment compared with the control group, but a large randomized trial would be needed to confirm this.