Endoscopy 2017; 49(04): 371-377
DOI: 10.1055/s-0042-120996
Innovations and brief communications
© Georg Thieme Verlag KG Stuttgart · New York

Clinical response to dorsal duct drainage via the minor papilla in refractory obstructing chronic calcific pancreatitis

Chang-Il Kwon
1   Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, USA
2   Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea
,
Mark A. Gromski
1   Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, USA
,
Stuart Sherman
1   Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, USA
,
Ihab I. El Hajj
1   Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, USA
,
Jeffrey J. Easler
1   Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, USA
,
James Watkins
1   Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, USA
,
Lee McHenry
1   Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, USA
,
Glen A. Lehman
1   Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, USA
,
Evan L. Fogel
1   Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, USA
› Author Affiliations
Further Information

Publication History

submitted 29 March 2016

accepted after revision 15 September 2016

Publication Date:
15 February 2017 (online)

Abstract

Background and study aims Complete stone removal from the main pancreatic duct might not be achieved in all patients with obstructive chronic calcific pancreatitis. We report our results for endoscopic dorsal pancreatic duct (DPD) bypass of obstructing stones in the ventral pancreatic duct (VPD).

Patients and methods 16 patients with obstructive chronic calcific pancreatitis were treated with a DPD bypass. Clinical success was defined as significant pain relief and no hospital admissions for pain management during the ongoing treatment period.

Results Among 16 patients meeting entry criteria, 10 (62.5 %) had a history of unsuccessful endoscopic therapy, and 8 had failed extracorporeal shockwave lithotripsy (ESWL). Clinical success was achieved in 12 patients (75 %). Among these responders, 10 patients (83.3 %) had markedly improved or complete pain relief after the first stent placement, which persisted throughout the follow-up period; 11 patients (91.7 %) were able to discontinue their daily analgesics.

Conclusions In selected patients with obstructive chronic calcific pancreatitis, the DPD bypass may be considered as a rescue endoscopic therapy, potentially obviating the need for surgery when standard endoscopic methods and ESWL fail.

 
  • References

  • 1 Sherman S, Lehman GA, Hawes RH. et al. Pancreatic ductal stones: frequency of successful endoscopic removal and improvement in symptoms. Gastrointest Endosc 1991; 37: 511-517
  • 2 Binmoeller KF, Jue P, Seifert H. et al. Endoscopic pancreatic stent drainage in chronic pancreatitis and a dominant stricture: long-term results. Endoscopy 1995; 27: 638-644
  • 3 Dumonceau JM, Devière J, Le Moine O. et al. Endoscopic pancreatic drainage in chronic pancreatitis associated with ductal stones: long-term results. Gastrointest Endosc 1996; 43: 547-555
  • 4 Rösch T, Daniel S, Scholz M. et al. Endoscopic treatment of chronic pancreatitis: a multicenter study of 1000 patients with long-term follow-up. Endoscopy 2002; 34: 765-771
  • 5 Delhaye M, Arvanitakis M, Verset G. et al. Long-term clinical outcome after endoscopic pancreatic ductal drainage for patients with painful chronic pancreatitis. Clin Gastroenterol Hepatol 2004; 2: 1096-1106
  • 6 Dumonceau JM. Endoscopic therapy for chronic pancreatitis. Gastrointest Endosc Clin N Am 2013; 23: 821-832
  • 7 Devière J. Chronic pancreatitis: stones and strictures. In: Baron TH, Kozarek RA, Carr-Locke DL. (eds.) ERCP. 2nd. edn. Philadelphia: Saunders; 2013
  • 8 Adler DG, Lichtenstein D, Baron TH. et al. The role of endoscopy in patients with chronic pancreatitis. Gastrointest Endosc 2006; 63: 933-937
  • 9 Song MH, Kim MH, Lee SK. et al. Endoscopic minor papilla interventions in patients without pancreas divisum. Gastrointest Endosc 2004; 59: 901-905
  • 10 Cotton PB, Lehman G, Vennes J. et al. Endoscopic sphincterotomy complications and their management: an attempt at consensus. Gastrointest Endosc 1991; 37: 383-393
  • 11 Costamagna G, Bulajic M, Tringali A. et al. Multiple stenting of refractory pancreatic duct strictures in severe chronic pancreatitis: long-term results. Endoscopy 2006; 38: 254-259