Raf Bisschops et al. Virtual chromoendoscopy (I-SCAN) detects more polyps in patients with Lynch syndrome: a randomized controlled crossover trial
This tandem colonoscopy trial compared the adenoma miss rate between I-SCAN digital chromoendoscopy and standard high definition white-light endoscopy in 61 patients with Lynch syndrome. I-SCAN colonoscopy resulted in a significantly lower adenoma miss rate of 12 % compared with 62 % using standard examination. The results support the use of image-enhanced endoscopy in these high risk patients.
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