Synlett 2023; 34(12): 1381-1384
DOI: 10.1055/s-0042-1752655
cluster
Special Issue Honoring Masahiro Murakami’s Contributions to Science

Nickel-Сatalyzed Carbon–Selenium Bond Formations under Mild Conditions

Serik Zhumagazy
,
Chen Zhu
,
Huifeng Yue
,
This work was financially supported by the King Abdullah University of Science and Technology (KAUST), Saudi Arabia, Office of Sponsored Research (URF/1/4405).


Abstract

A nickel-catalyzed C–Se cross-coupling between aryl iodides and selenols is described. The newly developed catalytic methodology offers facile access to various unsymmetrical selenium-containing motifs. The reaction features excellent functional group tolerance, wide substrate scope, good efficiency, and operates under mild reaction conditions. Notably, this protocol could be readily scaled up to gram scale without the loss of yield.

Supporting Information



Publication History

Received: 22 January 2023

Accepted after revision: 27 February 2023

Article published online:
31 March 2023

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