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Exp Clin Endocrinol Diabetes 2018; 126(02): 123-129
DOI: 10.1055/s-0043-112653
Article
© Georg Thieme Verlag KG Stuttgart · New York

Prevalence and Distribution of Diabetes Mellitus in a Maximum Care Hospital: Urgent Need for HbA1c-Screening

Johannes Kufeldt
1   Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology, and Clinical Chemistry, University Hospital Tuebingen, Tuebingen Germany
2   Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University Tuebingen, Tuebingen, Germany
,
Marketa Kovarova
1   Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology, and Clinical Chemistry, University Hospital Tuebingen, Tuebingen Germany
2   Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University Tuebingen, Tuebingen, Germany
3   German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
,
Michael Adolph
4   Department of Anaesthesiology and Intensive Care Medicine, University Hospital Tuebingen, Tuebingen, Germany
,
Harald Staiger
2   Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University Tuebingen, Tuebingen, Germany
3   German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
5   Institute of Pharmaceutical Sciences, Department of Pharmacy and Biochemistry, Eberhard Karls University Tuebingen
,
Michael Bamberg
6   Managing Medical Director and Chairman of the Board, University Hospital Tuebingen, Tuebingen, Germany
,
Hans-Ulrich Häring
1   Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology, and Clinical Chemistry, University Hospital Tuebingen, Tuebingen Germany
2   Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University Tuebingen, Tuebingen, Germany
3   German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
,
Andreas Fritsche   *
1   Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology, and Clinical Chemistry, University Hospital Tuebingen, Tuebingen Germany
2   Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University Tuebingen, Tuebingen, Germany
3   German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
,
Andreas Peter   *
1   Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology, and Clinical Chemistry, University Hospital Tuebingen, Tuebingen Germany
2   Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University Tuebingen, Tuebingen, Germany
3   German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
› Author Affiliations
Further Information

Publication History

received 13 April 2017
revised 13 April 2017

accepted 31 May 2017

Publication Date:
27 July 2017 (online)

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Abstract

Objective Diabetes mellitus affects almost one in 10 individuals in Germany. So far, little is known about the diabetes prevalence in maximum care hospitals. We assessed the diabetes prevalence, proportion of undiagnosed cases, the effectiveness of diabetes screening in a university hospital, the consequences for hospital stay and acquired complications.

Research Design and Methods Over a 4 week period we determined HbA1c from 3 733 adult patients which were hospitalized at the university hospital of Tuebingen and had an available blood sample. Diabetes diagnosis was defined as HbA1c≥6.5% and/or previously documented diabetes diagnosis, prediabetes was defined as HbA1c≥5.7% and <6.5% without history of previous diabetes.

Results 23.68% of the patients had prediabetes and 22.15% had diabetes with a high variation between the specialised departments (range 5–43%). The rate of unknown diabetes was 3.7%, the number needed to screen was 17 in patients older than 50 years. Patients with diabetes had a prolonged hospital stay compared to the mean length of stay for their diagnosis related group (diabetes: 1.47±0.24 days; no diabetes: −0.18±0.13 days, p=0.0133). The prevalence of hospital acquired complications was higher in diabetic patients (diabetes: 197 of 630; no diabetes: 447 of 2 459, p<0.0001).

Conclusions Every fourth patient in the university hospital had diabetes and every second had either prediabetes or diabetes. It is also worthwhile to screen for unknown diabetes in patients over the age of 50. The high prevalence and negative consequences of diabetes require screening and intensified specialized diabetes treatment in hospitals.

Key words

diabetes mellitus - diabetes prevalence - length of stay - complications - number needed to screen

* Andreas Fritsche and Andreas Peter contributed equally


 

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