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DOI: 10.1055/s-0043-116488
A third myotomy with peroral endoscopic myotomy after two failed Heller myotomies
Corresponding author
Publikationsverlauf
Publikationsdatum:
10. August 2017 (online)
Heller myotomy is the optimal surgical management for achalasia. Recurrent or persistent symptoms after surgical myotomy can occur in approximately 10 % of patients [1] [2].
Failed Heller myotomy presents a diagnostic and therapeutic challenge. An inadequate surgical myotomy is the commonest cause of failure. The appropriate treatment for failed surgical myotomy is controversial. Peroral endoscopic myotomy (POEM) is a novel procedure for treatment of achalasia. POEM has been shown to be effective and safe for the treatment of patients in whom prior surgical myotomy has failed. It is unclear which procedure should be utilized in patients with failed double Heller myotomy.
We report the case of a 79-year-old man who had type II achalasia despite undergoing transabdominal Heller myotomy with partial posterior fundoplication (May 2007). The therapeutic result of surgery was inadequate and he subsequently underwent transthoracic myotomy and partial division of the diaphragmatic crus (September 2007), followed by two courses (August 2008 and July 2009) of balloon dilation using a 20 mm controlled radial expansion balloon. There was a mild improvement in his symptoms (transient 10 % benefit at most according to the patient).
The patient underwent an extensive work-up, during which an esophagogastroduodenoscopy showed a dilated esophagus with retained secretion and tight lower esophageal sphincter (LES) ([Fig. 1 a]). The retroflexed view showed a sliding hiatal hernia ([Fig. 1 b]). Cine esophagram revealed a classic bird’s beak appearance ([Fig. 1 c]). High resolution esophageal manometry (HREM) confirmed type II achalasia. Multiple therapeutic options were discussed with the patient and he opted for POEM.
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Video 1 Clinical presentation and management of a patient with persistent symptoms after two failed Heller myotomies.
Qualität:
We elected to perform the standard POEM procedure (June 2016) along the posterior esophageal wall to avoid the submucosal fibrosis and scar from previous myotomies ([Fig. 2]). At the end of the procedure, the adequacy of POEM was grossly assessed by smooth passage of the scope though the gastroesophageal junction ([Fig. 3]) and intraoperative impedance planimetry ([Table 1]).
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POEM, peroral endoscopic myotomy; CSA, cross-sectional area.
Following POEM, the patient was admitted to the hospital and remained nil per os. The following morning, cine esophagram showed no leakage. He was discharged home on a soft diet. At follow-up, his Eckardt scores was 0. HREM at 6 months revealed significant decrease in LES pressure.
POEM should be considered as an option for rescue therapy after failed double Heller myotomies. Triple myotomy is technically feasible, appears to be safe, and has good short-term efficacy in refractory achalasia. Posterior myotomy is recommended to avoid the submucosal fibrosis and scars of previous surgical myotomies.
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Competing interests
Dr. Khashab is a consultant for Boston Scientific.
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References
- 1 Hunter JG, Trus TL, Branum GD. et al. Laparoscopic Heller myotomy and fundoplication for achalasia. Ann Surg 1997; 225: 655-664 discussion 664 – 655
- 2 Zaninotto G, Costantini M, Molena D. et al. Treatment of esophageal achalasia with laparoscopic Heller myotomy and Dor partial anterior fundoplication: prospective evaluation of 100 consecutive patients. J Gastrointest Surg 2000; 4: 282-289
Corresponding author
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References
- 1 Hunter JG, Trus TL, Branum GD. et al. Laparoscopic Heller myotomy and fundoplication for achalasia. Ann Surg 1997; 225: 655-664 discussion 664 – 655
- 2 Zaninotto G, Costantini M, Molena D. et al. Treatment of esophageal achalasia with laparoscopic Heller myotomy and Dor partial anterior fundoplication: prospective evaluation of 100 consecutive patients. J Gastrointest Surg 2000; 4: 282-289
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